The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphofructokinase domain
".
FunFam 8: ATP-dependent 6-phosphofructokinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P16861 (/IPI) P16861 (/IPI) P16861 (/IPI) P16861 (/IPI) P16861 (/IPI) P16862 (/IPI) |
6-phosphofructokinase activity GO:0003872
Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
|
5 | P90521 (/IGI) Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AK53 (/IGI) |
6-phosphofructokinase activity GO:0003872
Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
|
2 | O42938 (/IDA) P90521 (/IDA) |
6-phosphofructokinase activity GO:0003872
Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
|
2 | Q5B8A7 (/RCA) Q5B8A7 (/RCA) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | P16862 (/IDA) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | O42938 (/IDA) |
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
1 | P90521 (/IPI) |
Fructose-6-phosphate binding GO:0070095
Interacting selectively and non-covalently with fructose 6-phosphate.
|
1 | O42938 (/IDA) |
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
10 | P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16862 (/IGI) Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AK53 (/IGI) |
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
6 | P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16862 (/IDA) |
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
6 | P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16862 (/IMP) |
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
|
6 | P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16861 (/IMP) P16862 (/IMP) |
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
|
6 | P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16861 (/IGI) P16862 (/IGI) |
Micropexophagy GO:0000426
Degradation of a peroxisome by lysosomal microautophagy.
|
2 | Q92448 (/IMP) Q92448 (/IMP) |
Fructose 6-phosphate metabolic process GO:0006002
The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
|
2 | O42938 (/IDA) P90521 (/IDA) |
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
2 | Q5B8A7 (/RCA) Q5B8A7 (/RCA) |
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
|
2 | Q5B8A7 (/RCA) Q5B8A7 (/RCA) |
Peroxisome localization GO:0060151
Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
|
2 | Q92448 (/IMP) Q92448 (/IMP) |
Glycolytic process through fructose-6-phosphate GO:0061615
The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
|
2 | Q92448 (/IMP) Q92448 (/IMP) |
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
2 | Q92448 (/IMP) Q92448 (/IMP) |
Positive regulation of autophagosome maturation GO:1901098
Any process that activates or increases the frequency, rate or extent of autophagosome maturation.
|
2 | Q92448 (/IMP) Q92448 (/IMP) |
Glucose catabolic process GO:0006007
The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.
|
1 | P90521 (/IGI) |
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
|
1 | P16862 (/IMP) |
Fructose 1,6-bisphosphate metabolic process GO:0030388
The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
|
1 | O42938 (/IDA) |
Negative regulation of microtubule polymerization GO:0031115
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
|
1 | P90521 (/IDA) |
Canonical glycolysis GO:0061621
The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
|
1 | O42938 (/IC) |
Vacuolar proton-transporting V-type ATPase complex assembly GO:0070072
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
|
1 | P16862 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
6-phosphofructokinase complex GO:0005945
A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
|
8 | O42938 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16862 (/IDA) P90521 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | O42938 (/HDA) P16861 (/HDA) P16861 (/HDA) P16861 (/HDA) P16861 (/HDA) P16861 (/HDA) P16862 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16861 (/IDA) P16862 (/IDA) |
6-phosphofructokinase complex GO:0005945
A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
|
4 | Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AGZ8 (/IGI) Q5AK53 (/IGI) |
6-phosphofructokinase complex GO:0005945
A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
|
2 | Q92448 (/TAS) Q92448 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O42938 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P90521 (/IDA) |