The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"von Willebrand factor, type A domain
".
FunFam 20: protein transport protein Sec24D isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
|
6 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O94855 (/IPI) P53992 (/IPI) P53992 (/IPI) Q3V222 (/IPI) Q9SFU0 (/IPI) Q9SFU0 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
6 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) |
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
|
3 | O94855 (/IPI) P53992 (/IPI) P53992 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | O94855 (/IDA) P53992 (/IDA) P53992 (/IDA) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q9USS7 (/ISM) |
There are 37 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
7 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) Q9USS7 (/ISO) |
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
6 | A0A286YDI8 (/IMP) G3X972 (/IMP) Q3V222 (/IMP) Q6NXL1 (/IMP) Q80U83 (/IMP) Q8CGF4 (/IMP) |
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
6 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) |
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
|
4 | M9PC99 (/IMP) Q9SFU0 (/IMP) Q9SFU0 (/IMP) Q9VQ94 (/IMP) |
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
4 | M9PC99 (/IMP) Q9SFU0 (/IMP) Q9SFU0 (/IMP) Q9VQ94 (/IMP) |
Antigen processing and presentation of peptide antigen via MHC class I GO:0002474
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
3 | O94855 (/IMP) P53992 (/IMP) P53992 (/IMP) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
3 | O94855 (/NAS) P53992 (/NAS) P53992 (/NAS) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
Antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
3 | O94855 (/IDA) P53992 (/IDA) P53992 (/IDA) |
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Positive regulation of extracellular matrix constituent secretion GO:0003331
Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
|
2 | Q9SFU0 (/IMP) Q9SFU0 (/IMP) |
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Positive regulation of cell-cell adhesion GO:0022409
Any process that activates or increases the rate or extent of cell adhesion to another cell.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Negative regulation of DNA endoreduplication GO:0032876
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
|
2 | Q9SFU0 (/IMP) Q9SFU0 (/IMP) |
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Lumen formation, open tracheal system GO:0035149
Creation of the central hole of a tube in an open tracheal system through which gases flow.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Regulation of tube size, open tracheal system GO:0035151
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Regulation of tube diameter, open tracheal system GO:0035158
Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Chitin-based cuticle development GO:0040003
Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Positive regulation of cuticle pigmentation GO:0048081
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Male gamete generation GO:0048232
Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
|
2 | Q9SFU0 (/IMP) Q9SFU0 (/IMP) |
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
2 | D5LMH4 (/IMP) F1QRB4 (/IMP) |
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
|
2 | D5LMH4 (/IMP) F1QRB4 (/IMP) |
Extracellular matrix constituent secretion GO:0070278
The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.
|
2 | D5LMH4 (/IMP) F1QRB4 (/IMP) |
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
2 | M9PC99 (/IMP) Q9VQ94 (/IMP) |
ER body organization GO:0080119
A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.
|
2 | Q9SFU0 (/IMP) Q9SFU0 (/IMP) |
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
|
2 | M9PC99 (/ISS) Q9VQ94 (/ISS) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | Q9USS7 (/IC) |
Late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511
The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.
|
1 | Q9USS7 (/NAS) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
7 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) Q9USS7 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
ER to Golgi transport vesicle membrane GO:0012507
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
|
3 | O94855 (/TAS) P53992 (/TAS) P53992 (/TAS) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
3 | O94855 (/IDA) P53992 (/IDA) P53992 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
3 | O94855 (/NAS) P53992 (/NAS) P53992 (/NAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P53992 (/IDA) P53992 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
2 | M9PC99 (/ISS) Q9VQ94 (/ISS) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
2 | M9PC99 (/IDA) Q9VQ94 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9USS7 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9USS7 (/HDA) |