The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 948: Thymidine kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thymidine kinase activity GO:0004797
Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
4 Q38CF2 (/IMP) Q38CF2 (/IMP) Q8MX28 (/IMP) Q8MX28 (/IMP)
Thymidine kinase activity GO:0004797
Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
4 Q38CF2 (/ISM) Q38CF2 (/ISM) Q8MX28 (/ISM) Q8MX28 (/ISM)
Thymidine kinase activity GO:0004797
Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
3 F4KBF5 (/IDA) F4KBF5 (/IDA) Q9S750 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 F4KBF5 (/IPI) F4KBF5 (/IPI) Q9S750 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
4 Q38CF2 (/IMP) Q38CF2 (/IMP) Q8MX28 (/IMP) Q8MX28 (/IMP)
Pyrimidine deoxyribonucleotide salvage GO:0010139
The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.
4 Q38CF2 (/IMP) Q38CF2 (/IMP) Q8MX28 (/IMP) Q8MX28 (/IMP)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
4 Q38CF2 (/ISM) Q38CF2 (/ISM) Q8MX28 (/ISM) Q8MX28 (/ISM)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 F4KBF5 (/IMP) F4KBF5 (/IMP)
Seedling development GO:0090351
The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.
2 F4KBF5 (/IMP) F4KBF5 (/IMP)
Double-strand break repair GO:0006302
The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
1 Q9S750 (/IMP)
Response to UV-C GO:0010225
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
1 Q9S750 (/IEP)
Response to UV-C GO:0010225
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
1 Q9S750 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q38CF2 (/IDA) Q38CF2 (/IDA) Q8MX28 (/IDA) Q8MX28 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q38CF2 (/ISM) Q38CF2 (/ISM) Q8MX28 (/ISM) Q8MX28 (/ISM)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q38CF2 (/IDA) Q38CF2 (/IDA) Q8MX28 (/IDA) Q8MX28 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 F4KBF5 (/IDA) F4KBF5 (/IDA)
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