The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 84: Guanylate kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanylate kinase activity GO:0004385
Catalysis of the reaction: ATP + GMP = ADP + GDP.
190 E9PTV0 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA) P15454 (/IDA)
(180 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
149 P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA)
(139 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
13 P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA)
(3 more)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
13 P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA)
(3 more)
Guanylate kinase activity GO:0004385
Catalysis of the reaction: ATP + GMP = ADP + GDP.
13 P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P31006 (/ISS)
(3 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
13 P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA)
(3 more)
GMP binding GO:0019002
Interacting selectively and non-covalently with GMP, guanosine monophosphate.
13 P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA)
(3 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
13 P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA) P9WKE9 (/IDA)
(3 more)
Guanylate kinase activity GO:0004385
Catalysis of the reaction: ATP + GMP = ADP + GDP.
10 P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P46195 (/IMP)
Guanylate kinase activity GO:0004385
Catalysis of the reaction: ATP + GMP = ADP + GDP.
2 Q64520 (/ISO) Q64520 (/ISO)
Nucleoside monophosphate kinase activity GO:0050145
Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.
1 P31006 (/EXP)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DGDP phosphorylation GO:0006186
The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP.
15 Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA) Q8I2M1 (/IDA)
(5 more)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
10 P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P15454 (/ISS) P31006 (/ISS)
GDP biosynthetic process GO:0046711
The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.
9 P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP) P15454 (/IMP)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
3 Q9KNM4 (/ISS) Q9KNM4 (/ISS) Q9KNM4 (/ISS)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 Q64520 (/IDA) Q64520 (/IDA)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 Q64520 (/ISO) Q64520 (/ISO)
DGDP biosynthetic process GO:0006185
The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
DGDP biosynthetic process GO:0006185
The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
2 Q64520 (/ISO) Q64520 (/ISO)
GDP-mannose metabolic process GO:0019673
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
GDP-mannose metabolic process GO:0019673
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
2 Q64520 (/ISO) Q64520 (/ISO)
Glycoprotein transport GO:0034436
The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
Glycoprotein transport GO:0034436
The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q64520 (/ISO) Q64520 (/ISO)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
2 Q64520 (/ISO) Q64520 (/ISO)
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
GMP metabolic process GO:0046037
The chemical reactions and pathways involving GMP, guanosine monophosphate.
2 Q64520 (/ISO) Q64520 (/ISO)
DGMP metabolic process GO:0046054
The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
DGMP metabolic process GO:0046054
The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
2 Q64520 (/ISO) Q64520 (/ISO)
DATP metabolic process GO:0046060
The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
DATP metabolic process GO:0046060
The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
2 Q64520 (/ISO) Q64520 (/ISO)
GDP biosynthetic process GO:0046711
The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
GDP biosynthetic process GO:0046711
The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.
2 Q64520 (/ISO) Q64520 (/ISO)
Nucleotide phosphorylation GO:0046939
The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.
2 E9PTV0 (/IDA) Q71RR7 (/IDA)
Nucleotide phosphorylation GO:0046939
The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.
2 Q64520 (/ISO) Q64520 (/ISO)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 P46195 (/IMP)
Regulation of developmental growth GO:0048638
Any process that modulates the frequency, rate or extent of developmental growth.
1 Q94JM2 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
151 E9PTV0 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA) P60546 (/IDA)
(141 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA) P15454 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q64520 (/ISO) Q64520 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P31006 (/TAS)
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