The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 81: Preprotein translocase subunit SecA
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
66 |
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
(56 more) |
ATPase-coupled protein transmembrane transporter activity GO:0015462
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
59 |
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
P10408 (/IPI)
(49 more) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
7 | P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
7 | P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) P9WGP5 (/IDA) |
P-P-bond-hydrolysis-driven protein transmembrane transporter activity GO:0015450
Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
|
5 | Q81UI7 (/ISS) Q81UI7 (/ISS) Q81UI7 (/ISS) Q81X26 (/ISS) Q81X26 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein transport by the Sec complex GO:0043952
The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
|
66 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(56 more) |
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
59 |
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
(49 more) |
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
59 |
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
(49 more) |
Protein transport by the Sec complex GO:0043952
The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
|
59 |
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
(49 more) |
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Intracellular protein transmembrane transport GO:0065002
The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
|
59 |
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
P10408 (/IMP)
(49 more) |
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
12 |
Q81UI7 (/ISS)
Q81UI7 (/ISS)
Q81UI7 (/ISS)
Q81X26 (/ISS)
Q81X26 (/ISS)
Q9KPH4 (/ISS)
Q9KPH4 (/ISS)
Q9KPH4 (/ISS)
Q9KPH4 (/ISS)
Q9KPH4 (/ISS)
(2 more) |
Evasion or tolerance by symbiont of host-produced reactive oxygen species GO:0052059
The process in which an organism avoids the effects of reactive oxygen species produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
7 | P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) |
Protein secretion by the type II secretion system GO:0015628
The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.
|
3 | Q7CSN9 (/ISA) Q7CSN9 (/ISA) Q7CSN9 (/ISA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell envelope Sec protein transport complex GO:0031522
A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
|
66 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(56 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
59 |
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
P10408 (/IDA)
(49 more) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
7 | P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) |
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
|
7 | P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) P9WGP5 (/HDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) P9WGP5 (/TAS) |
Type II protein secretion system complex GO:0015627
A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
|
3 | Q7CSN9 (/ISA) Q7CSN9 (/ISA) Q7CSN9 (/ISA) |