The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 432: Voltage-dependent L-type calcium channel subunit b...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | F1R605 (/IPI) P19517 (/IPI) P54283 (/IPI) Q4KPD0 (/IPI) Q8R3Z5 (/IPI) |
|
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | F1R605 (/IMP) Q4KPD0 (/IMP) Q8R3Z5 (/IMP) |
|
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q8R3Z5 (/IDA) |
|
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q02641 (/IGI) |
|
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q8R3Z5 (/ISO) |
|
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q02641 (/TAS) |
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | Q9MZL7 (/IDA) |
|
High voltage-gated calcium channel activity GO:0008331
Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
|
1 | Q8R3Z5 (/IGI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P54283 (/IDA) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P54283 (/IPI) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | P54283 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P54283 (/IPI) |
|
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
|
1 | P54283 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
2 | F1R605 (/IMP) Q4KPD0 (/IMP) |
|
Voltage-gated calcium channel complex assembly GO:0070978
Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.
|
2 | F1R605 (/IMP) Q4KPD0 (/IMP) |
|
Protein targeting to membrane GO:0006612
The process of directing proteins towards a membrane, usually using signals contained within the protein.
|
1 | Q8R3Z5 (/IMP) |
|
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q8R3Z5 (/IMP) |
|
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
1 | Q02641 (/TAS) |
|
Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel GO:1902514
Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.
|
1 | Q02641 (/IGI) |
|
Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel GO:1902514
Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.
|
1 | Q8R3Z5 (/ISO) |
|
Cellular response to amyloid-beta GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
|
1 | Q02641 (/IGI) |
|
Cellular response to amyloid-beta GO:1904646
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.
|
1 | Q8R3Z5 (/ISO) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated calcium channel complex GO:0005891
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
|
4 | F1R605 (/IDA) P54283 (/IDA) Q4KPD0 (/IDA) Q8R3Z5 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q02641 (/TAS) Q8R3Z5 (/TAS) |
|
Voltage-gated calcium channel complex GO:0005891
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
|
2 | F1R605 (/IC) Q4KPD0 (/IC) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | F1R605 (/ISS) Q4KPD0 (/ISS) |
|
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
|
2 | P19517 (/IDA) Q8R3Z5 (/IDA) |
|
Voltage-gated calcium channel complex GO:0005891
A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
|
1 | Q02641 (/TAS) |
|
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
|
1 | Q8R3Z5 (/IDA) |
|
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | Q8R3Z5 (/IDA) |
|
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
|
1 | Q8R3Z5 (/IMP) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
1 | P54283 (/IDA) |
|
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
|
1 | P54283 (/IMP) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | P54283 (/IDA) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | P54283 (/IMP) |
|
L-type voltage-gated calcium channel complex GO:1990454
A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.
|
1 | P19517 (/IDA) |
