The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: ATP synthase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
237 P07677 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI) P0ABB4 (/IPI)
(227 more)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
180 P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP)
(170 more)
Proton-transporting ATP synthase activity, rotational mechanism GO:0046933
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.
9 Q55CS9 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
Proton-transporting ATP synthase activity, rotational mechanism GO:0046933
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.
6 Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q4Q9X5 (/ISO) Q4Q9X6 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q4Q9X5 (/ISO) Q4Q9X6 (/ISO)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
1 Q8T4C4 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP synthesis coupled proton transport GO:0015986
The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
10 Q55CS9 (/ISS) Q8T4C4 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
6 Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM) Q57XX1 (/ISM)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
3 P19366 (/IEP) P19366 (/IEP) P19366 (/IEP)
Defense response to fungus, incompatible interaction GO:0009817
A response of an organism to a fungus that prevents the occurrence or spread of disease.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 Q8T4C4 (/IMP)
Regulation of proton transport GO:0010155
Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8T4C4 (/IMP)
Response to mercury ion GO:0046689
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
1 Q55CS9 (/IDA)
Spermatid differentiation GO:0048515
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 Q8T4C4 (/IMP)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
1 Q8T4C4 (/ISS)

There are 32 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
180 P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA) P0ABB4 (/HDA)
(170 more)
Proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261
The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.
180 P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP) P0ABB4 (/IMP)
(170 more)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
56 P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS) P12085 (/ISS)
(46 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
15 P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA)
(5 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
15 P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA)
(5 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
15 P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA) P9WPU5 (/HDA)
(5 more)
Plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) GO:0045262
The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.
8 Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS) Q9KNH5 (/ISS)
Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) GO:0000275
The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
6 Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA) Q57XX1 (/RCA)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
6 Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA) Q57XX1 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Chloroplast thylakoid GO:0009534
Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Chloroplast thylakoid membrane GO:0009535
The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Chloroplast ATP synthase complex GO:0009544
The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts.
3 P19366 (/ISS) P19366 (/ISS) P19366 (/ISS)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Thylakoid GO:0009579
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Plastoglobule GO:0010287
A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Stromule GO:0010319
Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Thylakoid lumen GO:0031977
The volume enclosed by a thylakoid membrane.
3 P19366 (/IDA) P19366 (/IDA) P19366 (/IDA)
Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) GO:0000275
The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
2 Q4Q9X5 (/ISO) Q4Q9X6 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 Q4Q9X5 (/ISO) Q4Q9X6 (/ISO)
Plasma membrane proton-transporting ATP synthase complex GO:0045260
A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.
2 P26527 (/IDA) P26527 (/IDA)
Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) GO:0000275
The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
1 Q8T4C4 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q55CS9 (/ISS)
Mitochondrial proton-transporting ATP synthase, catalytic core GO:0005754
The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
1 Q55CS9 (/ISS)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q55CS9 (/HDA)
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