The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 286: ADP-ribosylation factor 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
138 P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS)
(128 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
138 P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI)
(128 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
138 P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS)
(128 more)
G-protein beta-subunit binding GO:0031681
Interacting selectively and non-covalently with a G-protein beta subunit.
69 G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA)
(59 more)
Thioesterase binding GO:0031996
Interacting selectively and non-covalently with any thioesterase enzyme.
69 P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI) P62330 (/IPI)
(59 more)
Thioesterase binding GO:0031996
Interacting selectively and non-covalently with any thioesterase enzyme.
69 P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO) P62331 (/ISO)
(59 more)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
69 P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI) P62331 (/IPI)
(59 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
6 P40946 (/ISS) P40946 (/ISS) P40946 (/ISS) P40946 (/ISS) P40946 (/ISS) P40946 (/ISS)
NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956
Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.
6 P40946 (/IDA) P40946 (/IDA) P40946 (/IDA) P40946 (/IDA) P40946 (/IDA) P40946 (/IDA)
Showing 1 to 9 of 9 entries

There are 77 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein localization to endosome GO:0036010
A process in which a protein is transported to, or maintained in, a location within an endosome.
207 P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS)
(197 more)
Endocytic recycling GO:0032456
The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.
138 P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA)
(128 more)
Protein localization to endosome GO:0036010
A process in which a protein is transported to, or maintained in, a location within an endosome.
138 P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP) P62330 (/IMP)
(128 more)
Regulation of dendritic spine development GO:0060998
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
138 P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP)
(128 more)
Regulation of dendritic spine development GO:0060998
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
138 P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS) P62330 (/ISS)
(128 more)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
69 P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP)
(59 more)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
69 P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS)
(59 more)
Regulation of neuron projection development GO:0010975
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
69 P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP) P62331 (/IMP)
(59 more)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
69 P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS) P62331 (/TAS)
(59 more)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
69 P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS)
(59 more)
Showing 1 to 10 of 77 entries

There are 50 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
282 G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA) G3N3N1 (/IDA)
(272 more)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
222 P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS)
(212 more)
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
207 P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS)
(197 more)
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
207 P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS)
(197 more)
Flemming body GO:0090543
A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
207 P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS) P62331 (/ISS)
(197 more)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
153 P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS)
(143 more)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
138 P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA)
(128 more)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
138 P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA) P62330 (/IDA)
(128 more)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
138 P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS) P62330 (/TAS)
(128 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
84 P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS) P26990 (/ISS)
(74 more)
Showing 1 to 10 of 50 entries
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