The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 268: ATP-dependent Clp protease, ATP-binding subunit Cl...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP-dependent peptidase activity GO:0004176
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds.
125 P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA)
(115 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
125 P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI) P0ABH9 (/IPI)
(115 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
125 P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA)
(115 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
125 P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP)
(115 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
125 P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA)
(115 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
9 Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
125 P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP)
(115 more)
Protein unfolding GO:0043335
The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.
125 P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP) P0ABH9 (/IMP)
(115 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
9 Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS) Q9KSW2 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
125 P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA) P0ABH9 (/IDA)
(115 more)
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