The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
3.40.50.2300
superfamily
Functional Families
Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
Superfamily: Response regulator
This superfamily comprises structural domains with a Rossmann fold found in a variety of proteins and enzymes, including response regulators such as LacI-like transcriptional regulators PMID:7973627,PMID:9865945, CheY-type chemotaxis response regulators INTERPRO:IPR011006,PMID:9030562,PMID:12080332, (multi-)sensor (hybrid) histidine kinase response regulators PMID:17005198, phosphate regulon response regulators (PhoP, PhoB), periplasmic binding proteins (PBPs) such as sugar-binding proteins PMID:17473016,PMID:19744923, ABC (ATP-binding cassette) transporters and other solute binding proteins (SBPs) PMID:23606130,PMID:23404400, histidine kinases, protein tyrosine phosphatases (kinases) PMID:21871460,PMID:24909685,PMID:11573087.
This domain can perform several functions such as ligand recognition, sugar binding, DNA binding, protein phosphorylation, chemotaxis, quorum sensing PMID:11823863, signal transduction.
Pfam clan [PfamClan:CL0144]
GO Diversity
Unique GO annotations
1325 Unique GO terms
EC Diversity
Unique EC annotations
32 Unique EC terms
Species Diversity
Unique species annotations
25789 Unique species
Sequence/Structure Diversity
Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.
Superfamily Summary
A general summary of information for this superfamily.
| Structures | |
|---|---|
| Domains: | 2543 |
| Domain clusters (>95% seq id): | 616 |
| Domain clusters (>35% seq id): | 402 |
| Unique PDBs: | 964 |
| Alignments | |
| Structural Clusters (5A): | 22 |
| Structural Clusters (9A): | 8 |
| FunFam Clusters: | 1676 |
| Function | |
| Unique EC: | 32 |
| Unique GO: | 1325 |
| Taxonomy | |
| Unique Species: | 25789 |
