The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Alcohol dehydrogenase, iron-containing

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
62 P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA)
(52 more)
Lactaldehyde reductase activity GO:0008912
Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.
62 P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA)
(52 more)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
29 P10127 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP) P37686 (/IMP)
(19 more)
L-threonine 3-dehydrogenase activity GO:0008743
Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH.
16 P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA) P37686 (/IDA)
(6 more)
Alcohol dehydrogenase activity, iron-dependent GO:0004025
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.
10 Q881D7 (/ISS) Q881D7 (/ISS) Q8EGV1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS)
1,3-propanediol dehydrogenase activity GO:0047516
Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.
5 P45513 (/IDA) P45513 (/IDA) P45513 (/IDA) P45513 (/IDA) P45513 (/IDA)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
4 P10127 (/IDA) Q04944 (/IDA) Q04944 (/IDA) Q04944 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 A0A0H2USH2 (/IPI) A0A0H2USH2 (/IPI) A0A0H2USH2 (/IPI)
Alcohol dehydrogenase activity, zinc-dependent GO:0004024
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
1 Q09669 (/ISO)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
1 Q8EGV1 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Rhamnose catabolic process GO:0019301
The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
62 P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP) P0A9S1 (/IEP)
(52 more)
L-fucose catabolic process GO:0042355
The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
62 P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP) P0A9S1 (/IMP)
(52 more)
Glycol catabolic process GO:0042846
The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
62 P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA)
(52 more)
Propanediol metabolic process GO:0051143
The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.
62 P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA)
(52 more)
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
10 Q881D7 (/ISS) Q881D7 (/ISS) Q8EGV1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS) Q9KLP1 (/ISS)
Amino acid catabolic process to alcohol via Ehrlich pathway GO:0000947
The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
1 P10127 (/IGI)
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
1 P10127 (/IMP)
Ethanol biosynthetic process involved in glucose fermentation to ethanol GO:0043458
The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP.
1 Q09669 (/IGI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
62 P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA) P0A9S1 (/IDA)
(52 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P10127 (/HDA) Q09669 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P10127 (/IDA)
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