View in Gene3D

CATH Superfamily 3.40.50.1820

Alpha/Beta hydrolase fold, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
alpha/beta hydrolase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 523: Pimeloyl-[acyl-carrier protein] methyl ester ester...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pimeloyl-[acyl-carrier protein] methyl ester esterase. [EC: 3.1.1.85]
Pimeloyl-[acyl-carrier protein] methyl ester + H(2)O = pimeloyl-[acyl- carrier protein] + methanol.
  • Involved in biotin biosynthesis in Gram-negative bacteria.
  • The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains.
  • Even though the enzyme can interact with coenzyme A thioesters, the in vivo role of the enzyme is to hydrolyze the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalyzed by the fatty acid elongation enzymes.
 10 A0A2A3LU84 A0A2A3LU84 A1KRU9 A1KRU9 E6MWF8 E6MWF8 Q5F641 Q9JSN0 Q9K197 Q9K197
CATH-Gene3D is a Global Biodata Core Resource Learn more...