The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Methylglyoxal synthase-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Carbamoyl-phosphate synthase large chain

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0004088
Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
12 P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA)
(2 more)
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity GO:0004088
Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
8 Q83C50 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS)
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
3 P00968 (/IMP) P00968 (/IMP) P00968 (/IMP)
Carbamoyl-phosphate synthase (ammonia) activity GO:0004087
Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P00968 (/IPI) P00968 (/IPI) P00968 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 P00968 (/IMP) P00968 (/IMP) P00968 (/IMP)
Amino acid binding GO:0016597
Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
Metal ion binding GO:0046872
Interacting selectively and non-covalently with any metal ion.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
12 P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA)
(2 more)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
12 P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA) P38100 (/IDA)
(2 more)
Pyrimidine ribonucleotide biosynthetic process GO:0009220
The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
8 Q83C50 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS) Q9KPH9 (/ISS)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
3 P00968 (/IMP) P00968 (/IMP) P00968 (/IMP)
Pyrimidine nucleobase biosynthetic process GO:0019856
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
3 P00968 (/IMP) P00968 (/IMP) P00968 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
Carbamoyl-phosphate synthase complex GO:0005951
A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
3 P00968 (/IDA) P00968 (/IDA) P00968 (/IDA)
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