The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
N-terminal domain of ligase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Acyl-coenzyme A synthetase ACSM2A, mitochondrialNon-ribosomal peptide synthetaseD-alanine--D-alanyl carrier protein ligaseNonribosomal siderophore peptide synthase SidCEnterobactin synthase component EAcetyl-coenzyme A synthetaseSC:2Phenylacetate-coenzyme A ligaseSC:3Acetyl-coenzyme A synthetase 2-like, mitochondrialAcetyl-coenzyme A synthetaseDisco interacting protein 2 homolog BLong-chain-fatty-acid--CoA ligase FadDDisco interacting protein 2 homolog ASolute carrier family 27 member 6long-chain-fatty-acid--CoA ligase 6 isoform X2Long-chain fatty acid transport protein 4Bifunctional protein AasLong-chain-fatty-acid--CoA ligase 4 isoform X1Long-chain-fatty-acid--AMP ligase FadD32Nonribosomal peptide synthetase 1Crotonobetaine/carnitine--CoA ligaseFatty acyl CoA synthetase 2Long-chain fatty acid transporterAcetyl-coenzyme A synthetaseLong-chain-fatty-acid--CoA ligase ACSBG1 isoform 1Acyl-CoA synthetaseLong-chain-fatty-acid--CoA ligase ACSBG1 isoform 1luciferin 4-monooxygenaseUncharacterized protein, isoform BAASDH isoform 4Long-chain-fatty-acid--CoA ligase 1Uncharacterized protein, isoform BAcyl-CoA synthetase family member 3Acyl--CoA ligaseLong-chain fatty acid--CoA ligase2-succinylbenzoate--CoA ligaseAcetoacetyl-CoA synthetaseAcyl-CoA synthetaseEbony proteinPeroxisomal-coenzyme A synthetaseAcyl-CoA synthetasevery long-chain-fatty-acid--CoA ligase bubblegumPossible fatty-acid-CoA ligase fadD1Acyl-CoA synthetaseShort-chain-fatty-acid--CoA ligaseAcetyl-CoA synthetase, putativeL-2-aminoadipate reductaseAcetyl-CoA synthetase, putativeCoenzyme A ligasePutative acyl-activating enzyme 19Acyl-CoA synthetaseAcyl-CoA synthetaseYOR093C-like proteinFatty-acid--CoA ligaseBifunctional fatty acid transporter/acyl-CoA synthetase (FAT1), putativeFatty-acid-CoA ligase FadD22Nonribosomal siderophore peptide synthase SidCPossible long-chain acyl-CoA synthaseAcetyl-coenzyme A synthetaseCoronamic acid synthetase CmaAAcyl-CoA synthetaseAcyl-CoA synthetaseNonribosomal peptide synthetase gliPAcetyl-coenzyme A synthetaseProbable medium chain fatty-acid-CoA ligase fadD14Fatty-acid-CoA ligase FadD34Probable fatty-acid-CoA ligase fadD6Probable chain-fatty-acid-CoA ligase fadD13Nonribosomal peptide synthase GliPYOR093C-like proteinYOR093C-like proteinLong-chain-fatty-acid--ACP ligase MbtMLong-chain-fatty-acid-CoA ligase, putativePutative long-chain-fatty-acid--CoA ligaseAcyl-CoA synthetase2-succinylbenzoate--CoA ligaseSalicyl-AMP ligase / salicyl-S-ArCP synthetasePutative long-chain-fatty-acid--CoA ligaseAcyl protein synthase/acyl-CoA reductase RfbNCapsule biosynthesis protein CapKNonribosomal peptide synthase SidEPossible fatty-acid-CoA ligase fadD10Fatty-acid-CoA ligase FadD2NRPS-like enzyme, putativeAnthranilate--CoA ligaseRfbL proteinO-succinylbenzoic acid--CoA ligaseAcetyl-CoA synthasePossible o-succinylbenzoic acid--CoA ligase menEAMP dependent ligase/synthetase, putativeLong-chain-fatty-acid--CoA ligase FadD15Putative long-chain-fatty-acid--CoA ligaseSolute carrier family 27 member 4Probable acyl-activating enzyme 18, peroxisomalAcyl-CoA synthetase, putativeAcyl-activating enzyme 15Peptide synthetase NrpAMP-dependent synthetase and ligaseLong-chain-fatty-acid--CoA ligaseFatty-acid-CoA ligase FadD9Nonribosomal peptide synthase Pes1Acetate-CoA ligase, putativeATP-dependent acyl-CoA ligase2-succinylbenzoate--CoA ligaseOchratoxin A non-ribosomal peptide synthetasePutative long-chain-fatty-acid-CoA ligasePutative fatty-acid--CoA ligase fadD11Putative fatty-acid--CoA ligase fadD11NonRibosomal Peptide SynthetaseProbable non-ribosomal peptide synthetaseNonribosomal peptide synthase, putativeNonribosomal peptide synthase GliP2Nonribosomal peptide synthase, putativeBeta-alanine-activating enzymeAspergillus niger contig An11c0010, genomic contigNon-ribosomal peptide synthetasesolute carrier family 27 member 3 isoform X1Acyl-CoA synthetase medium chain family member 5Acetyl-coenzyme A synthetaseAM-toxin synthetaseUncharacterized proteinAcyl-CoA synthetaseHydroxamate-type ferrichrome siderophore peptide synthetaseNonribosomal peptide synthetase fmqCIsocyanide synthase-NRPS hybrid crmAPKS-NRPS hybrid synthetase psoANonribosomal peptide synthetase 8Nonribosomal peptide synthase, putativeFatty acid transporter, putative2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomalUncharacterized proteinAcyl-CoA synthetase8-demethylnovobiocic acid synthaseD-alanine--poly(Phosphoribitol) ligaseATP-dependent acyl-CoA ligaseNonribosomal peptide synthetase, discrete adenylation domainL-prolyl-AMP Ligase PltFProbable L-prolyl-AMP ligase PigIUncharacterized proteinAMP dependent CoA ligase, putativeAcetyl-CoA synthetase (Acetate-CoA ligase) amino-end (AcsA-4)AMP-binding enzyme, putative (AFU_orthologue AFUA_5G04270)Uncharacterized proteinUncharacterized proteinNRPS-like enzyme, putative (AFU_orthologue AFUA_8G01222)NRPS-like enzyme, putative (AFU_orthologue AFUA_8G01222)Uncharacterized proteinChromosome 19, whole genome shotgun sequenceChromosome 19, whole genome shotgun sequenceNonribosomal peptide synthase Pes1 (Eurofung)Enniatin synthaseUncharacterized proteinNRPS-like enzyme, putative (JCVI)Putative pantothenate kinase subunitNonribosomal peptide synthase, putative (JCVI)AMP-binding enzyme, putativeNonribosomal peptide synthase nlsANatural product biosynthesis luciferase-like monooxygenase domain-containing proteinNonribosomal peptide synthase nlsANRPS-like enzyme, putativeNonribosomal peptide synthase, putative (JCVI)Putative siderophore synthetase (Eurofung)HC-toxin synthetaseNonribosomal peptide synthase nlsALong-chain fatty acid transport protein 1Uncharacterized proteinChromosome 19, whole genome shotgun sequenceMeiotically up-regulated gene 62 proteinBenzoate-coenzyme A ligase, putativePutative acetyl-CoA synethetaseSA proteinPutative long-chain fatty-acid-CoA ligaseLong-chain-fatty-acid--CoA ligase, putativePredicted proteinUncharacterized proteinLong-chain-fatty-acid-coA ligase protein,putativeUncharacterized proteinLP07340pUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinAcetyl-CoA synthetase (Acetate-CoA ligase) carboxy-end (AcsA-4)Uncharacterized proteinUncharacterized proteinMIP16841pUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAMP dependent CoA ligase, putativeUncharacterized proteinUncharacterized proteinAMP-binding proteinUncharacterized proteinFirefly luciferase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinSolute carrier family 27 member 2Uncharacterized proteinLong-chain-fatty-acid--luciferin-component ligaseUncharacterized proteinFatty acid transporter protein-like proteinProbable auxin-responsive-like proteinPredicted proteinAcyl-CoA synthetase, putativeFolliculin-interacting protein 1Uncharacterized proteinPutative long-chain-fatty-acid-CoA ligaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPutative long-chain-fatty-acid-CoA ligaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDisco interacting protein 2 homolog AHydroxamate-type ferrichrome siderophore peptide synthetaseUncharacterized proteinPantothenate kinase subunit, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinMutant e4 ebonyUncharacterized proteinPredicted proteinUncharacterized protein C56F8.02Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMutant e4 ebonyUncharacterized proteinUncharacterized protein C162.02c
« Back to all FunFams

FunFam 50: Acyl-CoA synthetase

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

CATH-Gene3D is a Global Biodata Core Resource Learn more...