The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
N-terminal domain of ligase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Acyl-coenzyme A synthetase ACSM2A, mitochondrialNon-ribosomal peptide synthetaseD-alanine--D-alanyl carrier protein ligaseNonribosomal siderophore peptide synthase SidCEnterobactin synthase component EAcetyl-coenzyme A synthetaseSC:2Phenylacetate-coenzyme A ligaseSC:3Acetyl-coenzyme A synthetase 2-like, mitochondrialAcetyl-coenzyme A synthetaseDisco interacting protein 2 homolog BLong-chain-fatty-acid--CoA ligase FadDDisco interacting protein 2 homolog ASolute carrier family 27 member 6long-chain-fatty-acid--CoA ligase 6 isoform X2Long-chain fatty acid transport protein 4Bifunctional protein AasLong-chain-fatty-acid--CoA ligase 4 isoform X1Long-chain-fatty-acid--AMP ligase FadD32Nonribosomal peptide synthetase 1Crotonobetaine/carnitine--CoA ligaseFatty acyl CoA synthetase 2Long-chain fatty acid transporterAcetyl-coenzyme A synthetaseLong-chain-fatty-acid--CoA ligase ACSBG1 isoform 1Acyl-CoA synthetaseLong-chain-fatty-acid--CoA ligase ACSBG1 isoform 1luciferin 4-monooxygenaseUncharacterized protein, isoform BAASDH isoform 4Long-chain-fatty-acid--CoA ligase 1Uncharacterized protein, isoform BAcyl-CoA synthetase family member 3Acyl--CoA ligaseLong-chain fatty acid--CoA ligase2-succinylbenzoate--CoA ligaseAcetoacetyl-CoA synthetaseAcyl-CoA synthetaseEbony proteinPeroxisomal-coenzyme A synthetaseAcyl-CoA synthetasevery long-chain-fatty-acid--CoA ligase bubblegumPossible fatty-acid-CoA ligase fadD1Acyl-CoA synthetaseShort-chain-fatty-acid--CoA ligaseAcetyl-CoA synthetase, putativeL-2-aminoadipate reductaseAcetyl-CoA synthetase, putativeCoenzyme A ligasePutative acyl-activating enzyme 19Acyl-CoA synthetaseAcyl-CoA synthetaseYOR093C-like proteinFatty-acid--CoA ligaseBifunctional fatty acid transporter/acyl-CoA synthetase (FAT1), putativeFatty-acid-CoA ligase FadD22Nonribosomal siderophore peptide synthase SidCPossible long-chain acyl-CoA synthaseAcetyl-coenzyme A synthetaseCoronamic acid synthetase CmaAAcyl-CoA synthetaseAcyl-CoA synthetaseNonribosomal peptide synthetase gliPAcetyl-coenzyme A synthetaseProbable medium chain fatty-acid-CoA ligase fadD14Fatty-acid-CoA ligase FadD34Probable fatty-acid-CoA ligase fadD6Probable chain-fatty-acid-CoA ligase fadD13Nonribosomal peptide synthase GliPYOR093C-like proteinYOR093C-like proteinLong-chain-fatty-acid--ACP ligase MbtMLong-chain-fatty-acid-CoA ligase, putativePutative long-chain-fatty-acid--CoA ligaseAcyl-CoA synthetase2-succinylbenzoate--CoA ligaseSalicyl-AMP ligase / salicyl-S-ArCP synthetasePutative long-chain-fatty-acid--CoA ligaseAcyl protein synthase/acyl-CoA reductase RfbNCapsule biosynthesis protein CapKNonribosomal peptide synthase SidEPossible fatty-acid-CoA ligase fadD10Fatty-acid-CoA ligase FadD2NRPS-like enzyme, putativeAnthranilate--CoA ligaseRfbL proteinO-succinylbenzoic acid--CoA ligaseAcetyl-CoA synthasePossible o-succinylbenzoic acid--CoA ligase menEAMP dependent ligase/synthetase, putativeLong-chain-fatty-acid--CoA ligase FadD15Putative long-chain-fatty-acid--CoA ligaseSolute carrier family 27 member 4Probable acyl-activating enzyme 18, peroxisomalAcyl-CoA synthetase, putativeAcyl-activating enzyme 15Peptide synthetase NrpAMP-dependent synthetase and ligaseLong-chain-fatty-acid--CoA ligaseFatty-acid-CoA ligase FadD9Nonribosomal peptide synthase Pes1Acetate-CoA ligase, putativeATP-dependent acyl-CoA ligase2-succinylbenzoate--CoA ligaseOchratoxin A non-ribosomal peptide synthetasePutative long-chain-fatty-acid-CoA ligasePutative fatty-acid--CoA ligase fadD11Putative fatty-acid--CoA ligase fadD11NonRibosomal Peptide SynthetaseProbable non-ribosomal peptide synthetaseNonribosomal peptide synthase, putativeNonribosomal peptide synthase GliP2Nonribosomal peptide synthase, putativeBeta-alanine-activating enzymeAspergillus niger contig An11c0010, genomic contigNon-ribosomal peptide synthetasesolute carrier family 27 member 3 isoform X1Acyl-CoA synthetase medium chain family member 5Acetyl-coenzyme A synthetaseAM-toxin synthetaseUncharacterized proteinAcyl-CoA synthetaseHydroxamate-type ferrichrome siderophore peptide synthetaseNonribosomal peptide synthetase fmqCIsocyanide synthase-NRPS hybrid crmAPKS-NRPS hybrid synthetase psoANonribosomal peptide synthetase 8Nonribosomal peptide synthase, putativeFatty acid transporter, putative2-succinylbenzoate--CoA ligase, chloroplastic/peroxisomalUncharacterized proteinAcyl-CoA synthetase8-demethylnovobiocic acid synthaseD-alanine--poly(Phosphoribitol) ligaseATP-dependent acyl-CoA ligaseNonribosomal peptide synthetase, discrete adenylation domainL-prolyl-AMP Ligase PltFProbable L-prolyl-AMP ligase PigIUncharacterized proteinAMP dependent CoA ligase, putativeAcetyl-CoA synthetase (Acetate-CoA ligase) amino-end (AcsA-4)AMP-binding enzyme, putative (AFU_orthologue AFUA_5G04270)Uncharacterized proteinUncharacterized proteinNRPS-like enzyme, putative (AFU_orthologue AFUA_8G01222)NRPS-like enzyme, putative (AFU_orthologue AFUA_8G01222)Uncharacterized proteinChromosome 19, whole genome shotgun sequenceChromosome 19, whole genome shotgun sequenceNonribosomal peptide synthase Pes1 (Eurofung)Enniatin synthaseUncharacterized proteinNRPS-like enzyme, putative (JCVI)Putative pantothenate kinase subunitNonribosomal peptide synthase, putative (JCVI)AMP-binding enzyme, putativeNonribosomal peptide synthase nlsANatural product biosynthesis luciferase-like monooxygenase domain-containing proteinNonribosomal peptide synthase nlsANRPS-like enzyme, putativeNonribosomal peptide synthase, putative (JCVI)Putative siderophore synthetase (Eurofung)HC-toxin synthetaseNonribosomal peptide synthase nlsALong-chain fatty acid transport protein 1Uncharacterized proteinChromosome 19, whole genome shotgun sequenceMeiotically up-regulated gene 62 proteinBenzoate-coenzyme A ligase, putativePutative acetyl-CoA synethetaseSA proteinPutative long-chain fatty-acid-CoA ligaseLong-chain-fatty-acid--CoA ligase, putativePredicted proteinUncharacterized proteinLong-chain-fatty-acid-coA ligase protein,putativeUncharacterized proteinLP07340pUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinAcetyl-CoA synthetase (Acetate-CoA ligase) carboxy-end (AcsA-4)Uncharacterized proteinUncharacterized proteinMIP16841pUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAMP dependent CoA ligase, putativeUncharacterized proteinUncharacterized proteinAMP-binding proteinUncharacterized proteinFirefly luciferase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinSolute carrier family 27 member 2Uncharacterized proteinLong-chain-fatty-acid--luciferin-component ligaseUncharacterized proteinFatty acid transporter protein-like proteinProbable auxin-responsive-like proteinPredicted proteinAcyl-CoA synthetase, putativeFolliculin-interacting protein 1Uncharacterized proteinPutative long-chain-fatty-acid-CoA ligaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPutative long-chain-fatty-acid-CoA ligaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinDisco interacting protein 2 homolog AHydroxamate-type ferrichrome siderophore peptide synthetaseUncharacterized proteinPantothenate kinase subunit, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinMutant e4 ebonyUncharacterized proteinPredicted proteinUncharacterized protein C56F8.02Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMutant e4 ebonyUncharacterized proteinUncharacterized protein C162.02c
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FunFam 37: Acyl-CoA synthetase

GO Diversity

Unique GO annotations
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EC Diversity

Unique EC annotations
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Species Diversity

Unique species annotations
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Statistics

Members
CATH Domains: 0
Sequences: 25
Annotations
Unique GO: 5
Unique EC: 0
Unique Species: 15
Representative
Rep ID: O96230/376-546_590-730
Inherited Annotations: 0
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