CATH Superfamily 3.40.50.12550

Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2
".

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Superfamily 3.40.50.12550

3.40.50.12550

superfamily

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Summary
Superfamily Superposition
Classification / Domains
Functional Families
Structural Neighbourhood

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2

The adenylation domains composed of two MoeB/ThiF-homology motifs (hereafter, IAD and AAD, for 'inactive' and 'active' adenylation domain, respectively), the latter of which binds ATP and Ub.

DOI:10.1016/j.molcel.2013.01.013

GO Diversity

Unique GO annotations

58 Unique GO terms

EC Diversity

Unique EC annotations

1 Unique EC terms

Species Diversity

Unique species annotations

1492 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.

Structures
Domains:	19
Domain clusters (>95% seq id):	3
Domain clusters (>35% seq id):	1
Unique PDBs:	10
Alignments
Structural Clusters (5A):	1
Structural Clusters (9A):	1
FunFam Clusters:	17
Function
Unique EC:	1
Unique GO:	58
Taxonomy
Unique Species:	1492