The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hydroxymethylbutenyl pyrophosphate reductase activity GO:0042380
Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
114 P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA)
(104 more)
3 iron, 4 sulfur cluster binding GO:0051538
Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
114 P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA)
(104 more)
4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity GO:0051745
Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
12 Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA)
(2 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0019288
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
114 P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP) P62623 (/IMP)
(104 more)
Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway GO:0019288
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
12 Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA)
(2 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
114 P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA) P62623 (/IDA)
(104 more)
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
12 Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA) Q8I295 (/IDA)
(2 more)
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