CATH Superfamily 3.40.50.10990

FunFam 2: GTP cyclohydrolase-2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term	Annotations	Evidence
GTP cyclohydrolase II. [EC: 3.5.4.25] GTP + 3 H(2)O = formate + 2,5-diamino-6-hydroxy-4-(5-phospho-D- ribosylamino)pyrimidine + diphosphate. Two C-N bonds are hydrolyzed, releasing formate, with simultaneous removal of the terminal diphosphate.	21911	A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 A0A023YWM6 (21901 more...)
3,4-dihydroxy-2-butanone-4-phosphate synthase. [EC: 4.1.99.12] D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate. The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5. The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin.	95	A0A0B6XPY3 A0A0B6XPY3 A0A0B6XPY3 A0A0B6XPY3 A0A0B6XPY3 A0A0D6HB31 A0A0D6HB31 A0A0D6HB31 A0A0D6HB31 A0A0D6HB31 (85 more...)

Functional Families

There are 2 EC terms in this cluster