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CATH Superfamily 3.40.50.10810

Tandem AAA-ATPase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Tandem AAA-ATPase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Chromodomain-helicase-DNA-binding protein 2 isoform 1DNA repair and recombination protein RAD54-likeRNA polymerase-associated protein RapADNA helicase, SNF2/RAD54 familychromodomain-helicase-DNA-binding protein 3 isoform X1ISWI chromatin-remodeling complex ATPase CHR11 isoform Achromodomain-helicase-DNA-binding protein 8 isoform X4probable global transcription activator SNF2L2 isoform X1Photoperiod-independent early flowering 1Putative DNA helicase INO80Chromatin structure-remodeling complex subunit snf21B-TFIID TATA-box-binding protein-associated factor 1Transcriptional regulator ATRX homologE3 ubiquitin-protein ligase SHPRH isoform X2SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1lymphoid-specific helicase isoform X1Chromatin structure-remodeling complex protein SYDATP-dependent helicase BRMPutative DNA excision repair protein ERCC-6DNA excision repair protein ERCC-6-like 2 isoform X1DNA repair and recombination protein RAD54BDNA repair and recombination protein RAD54Blast:Putative DNA helicase Ino80helicase-like transcription factor isoform X1DNA annealing helicase and endonuclease ZRANB3E3 ubiquitin-protein ligase SHPRH isoform X1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1helicase-like transcription factor isoform X3Chromatin-remodeling complex ATPaseERCC excision repair 6-like, spindle assembly checkpoint helicaseATP-dependent DNA helicase DDM1Helicase, SNF2/RAD54 familyHelicase ARIP4E1A-binding protein p400 isoform X9Protein CHROMATIN REMODELING 8DsDNA-dependent ATPase (Rad54b)Chromatin remodelling complex ATPase chainchromodomain-helicase-DNA-binding protein 1-like isoform X1Protein CHROMATIN REMODELING 19 isoform ADNA repair protein Rhp26/Rad26Switch 2Chromatin remodeling proteinSNF2 family helicase-like proteinTranscription termination factor 2Chromatin remodeling factor18Putative chromatin-remodeling complex ATPase chainPutative SNF2 family helicase/ATPaseDEAD/DEAH box helicaseSNF2 helicase, putativeDNA helicaseSnf2-related CBP activatorHelicase SWR1DNA helicaseSNF2 family helicase/ATPase, putativeHelicase, Snf2 familyProtein CHROMATIN REMODELING 24DNA repair protein RAD5Snf2/Rad54 family helicaseRDH54p DNA-dependent ATPaseSNF2 family helicase/ATPase, putativeDNA repair protein RAD5DNA repair protein rhp16DNA repair protein rhp16Chromosome 12, whole genome shotgun sequenceSWI/SNF family DNA-dependent ATPase Ris1, putativeSNF2 DNA repair protein, putativeUncharacterized protein (Fragment)ATP-dependent DNA helicaseSNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-like proteinDNA helicaseDNA helicase, putativeSNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-like proteinBifunctional helicase and thymine dioxygenase JBP2DNA helicase, putativeDNA dependent ATPase, putativeProtein CHROMATIN REMODELING 5ATP-dependent helicase ULS1Putative DNA repair proteinHelicase domain containing proteinSWF/SNF family helicaseDNA repair protein RAD16DNA repair protein, putativeSNF2 domain-containing proteinHelicase putativeProtein CHROMATIN REMODELING 19Transcription regulatory protein SNF2CHD3-type chromatin-remodeling factor PICKLEChromatin remodeling 38Irc20pDNA repair protein RAD5BSimilarity to HELICASE MOT1Protein CHROMATIN REMODELING 4DNA repair protein rhp16, putativeDNA excision repair protein ERCC-6Helicase, putativeHelicase, putativeUncharacterized protein, isoform AUncharacterized protein, isoform ARad5pSNF2 family proteinSWI/SNF-related, matrix-associated, actin-dependent regulator ofChromosome organization and biogenesis-related protein, putativeDNA repair and recombination protein RAD54B, putativeProtein CHROMATIN REMODELING 20DNA repair protein, putativeProbable global transcription activator SNF2L2SNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-like proteinHelicase superfamily, c-terminal domain proteinSNF2 domain-containing protein CLASSY 4Putative SNF2 family helicaseUnplaced genomic scaffold supercont1.14, whole genome shotgun sequenceSuURPutative snf2 family helicase atpase proteinDNA repair protein rad8Nucleosome remodeling complex ATPase subunit (Snf2h)SNF2 family helicase, putativeDefense against restriction protein BDefense against restriction protein BCSB (Cockayne Syndrome B) homologSNF2 family N-terminal domain/Helicase conserved C-terminal domain containing protein, putativeDNA repair and recombination protein RAD54BUncharacterized proteinUncharacterized proteinRAD54 likeHelicase, Snf2 family proteinDNA helicaseHelicase SNF2SNF2_family_N-terminal_domain /Helicase_conserved_C-terminal_domain_containing_protein_-_putativeSWF/SNF family helicaseWGS project CABT00000000 data, contig 2.20AGAP010699-PAExcision repair cross-complementation group 6-like 2SNF2 histone linker PHD RING helicaseUncharacterized proteinUncharacterized proteinSNF2 family N-terminal domain-domain-containing proteinHelicase-like proteinProtein CHROMATIN REMODELING 35ATP-dependent helicase, putativeDNA repair and recombination protein Rhp26pUncharacterized proteinRAD54B DNA helicase splice variantEukaryotic translation initiation factor 3 subunit ESNF2 family N-terminal domain-domain-containing proteinSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1RAD54L isoform 5RAD54 likeCHD gene family protein containing chromodomain, helicase domain, and DNA-binding domainSnf2-related CREBBP activator proteinHelicase, putativeSnf2-related CREBBP activator proteinProtein CBG00336Helicase, putativeSNF2 histone linker PHD RING helicaseUncharacterized proteinUncharacterized proteinPutative SNF2 family helicaseUncharacterized proteinPredicted proteinHelicaseSNF2 family N-terminal domain-domain-containing proteinPutative snf2 family dna-dependent atpase domain-containing proteinPutative DNA excision/repair protein SNF2Uncharacterized proteinExcision repair cross-complementing rodent repair deficiency, complementation group 6 variantUncharacterized proteinSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily-related, putativeDNA repair and recombination protein RAD54B, putativePredicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized protein, isoform EUncharacterized protein, isoform EDNA excision repair protein ERCC-6SNF2 superfamily proteinSNF2 superfamily proteinHelicase superfamily, c-terminal domain proteinp-loop containing nucleoside triphosphate hydrolase proteinSnf2 family helicaseATP-dependent helicase HepAp-loop containing nucleoside triphosphate hydrolase proteinHelicase superfamily, c-terminal domain proteinSWI/SNF family DNA-dependent ATPase, putativeSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1SWF/SNF family helicasePredicted proteinUncharacterized proteinSNF2 superfamily proteinExcision repair cross-complementation group 6-likePredicted proteinChromodomain helicase DNA-binding protein 3Uncharacterized proteinUncharacterized proteinE3 ubiquitin-protein ligase SHPRH-like ProteinPredicted proteinAdenosinetriphosphataseDNA repair protein, putativeProtein CBR-RAD-54Uncharacterized proteinSNF2 family DNA-dependent ATPaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinDNA repair protein, putativeUncharacterized proteinSWI/SNF chromatin remodeling complex componentUncharacterized proteinUncharacterized proteinSWI/SNF chromatin remodeling complex componentProtein CBG05712Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAEL297WpE3 ubiquitin-protein ligase SHPRH-like ProteinProtein CBR-RAD-54Uncharacterized proteinSNF2 histone linker PHD RING helicaseDNA repair protein RAD5AUncharacterized proteinERCC excision repair 6, chromatin remodeling factorSNF2 DNA repair protein, putativeType III restriction enzyme, res subunit family proteinUncharacterized ATP-dependent helicase MG018Uncharacterized proteinType III restriction enzyme, res subunit family proteinSwi/snf family helicase_2Uncharacterized proteinProtein CHROMATIN REMODELING 24Predicted proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinERCC excision repair 6, chromatin-remodeling factorSNF2 family N-terminal domain containing proteinPredicted proteinUncharacterized proteinDNA repair protein-like proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinSnf2 histone linker PHD ring helicase, putativeUncharacterized proteinUncharacterized proteinExcision repair cross-complementing rodent repair deficiency, complementation group 6Predicted proteinChromosome 10, whole genome shotgun sequenceUncharacterized proteinMeiotic recombination protein rdh54Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized ATP-dependent helicase C17A2.12Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSNF2/RAD54 family proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 12: RNA polymerase-associated protein RapA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Bacterial-type RNA polymerase core enzyme binding GO:0001000
Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.
 80 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(70 more)
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
 80 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(70 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 80 P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI) P60240 (/IPI)
(70 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
 80 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(70 more)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)
Showing 1 to 6 of 6 entries

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 80 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(70 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
 5 Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS) Q9KP70 (/ISS)
Showing 1 to 2 of 2 entries

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 80 P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA) P60240 (/IDA)
(70 more)
Showing 1 to 1 of 1 entries
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