The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Dihydroxyacetone kinase; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Dihydroxyacetone kinase, DhaK subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-glycerone phosphotransferase activity GO:0047324
Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
26 P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS) P76015 (/ISS)
(16 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
25 P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI)
(15 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
21 P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI) P76015 (/IPI)
(11 more)
Phosphoenolpyruvate-glycerone phosphotransferase activity GO:0047324
Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
21 P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP)
(11 more)
Phosphoenolpyruvate-glycerone phosphotransferase activity GO:0047324
Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
4 Q92EU2 (/IDA) Q92EU2 (/IDA) Q92EU2 (/IDA) Q92EU2 (/IDA)
Triokinase activity GO:0050354
Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).
4 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q8VC30 (/IDA)
Glycerone kinase activity GO:0004371
Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+).
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
FAD-AMP lyase (cyclizing) activity GO:0034012
Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
Glycerone kinase activity GO:0004371
Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+).
1 Q8VC30 (/ISO)
FAD-AMP lyase (cyclizing) activity GO:0034012
Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.
1 Q8VC30 (/ISO)
Triokinase activity GO:0050354
Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).
1 Q8VC30 (/ISO)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
21 P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP) P76015 (/IEP)
(11 more)
Ketone catabolic process GO:0042182
The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
21 P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP)
(11 more)
Monosaccharide catabolic process GO:0046365
The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
21 P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP)
(11 more)
Glycerol to glycerone phosphate metabolic process GO:0061610
The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.
21 P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP) P76015 (/IMP)
(11 more)
Negative regulation of MDA-5 signaling pathway GO:0039534
Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
4 F1RKQ4 (/ISS) Q4KLZ6 (/ISS) Q58DK4 (/ISS) Q8VC30 (/ISS)
Negative regulation of MDA-5 signaling pathway GO:0039534
Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
Cellular carbohydrate metabolic process GO:0044262
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
3 Q3LXA3 (/TAS) Q3LXA3 (/TAS) Q3LXA3 (/TAS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
Carbohydrate phosphorylation GO:0046835
The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.
3 Q3LXA3 (/IDA) Q3LXA3 (/IDA) Q3LXA3 (/IDA)
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
3 Q3LXA3 (/TAS) Q3LXA3 (/TAS) Q3LXA3 (/TAS)
Negative regulation of MDA-5 signaling pathway GO:0039534
Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
1 Q8VC30 (/ISO)
Cellular carbohydrate metabolic process GO:0044262
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
1 Q8VC30 (/ISO)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q8VC30 (/ISO)
Carbohydrate phosphorylation GO:0046835
The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.
1 Q8VC30 (/ISO)
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate GO:0061624
The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
1 Q8VC30 (/IC)
Glycolytic process through fructose-1-phosphate GO:0061625
The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.
1 Q8VC30 (/IC)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA) P76015 (/HDA)
(11 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
21 P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA) P76015 (/IDA)
(11 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q3LXA3 (/HDA) Q3LXA3 (/HDA) Q3LXA3 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q3LXA3 (/TAS) Q3LXA3 (/TAS) Q3LXA3 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 Q3LXA3 (/HDA) Q3LXA3 (/HDA) Q3LXA3 (/HDA)
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