The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Malic enzyme, N-terminal domain
".
FunFam 8: Malic enzyme
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
7 | Q2QBM1 (/IMP) Q9NIW0 (/IMP) Q9NIW1 (/IMP) Q9NIW2 (/IMP) Q9U1J1 (/IMP) Q9VG31 (/IMP) Q9VG32 (/IMP) |
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
4 | E1JIZ4 (/ISS) E1JIZ5 (/ISS) Q9U1J0 (/ISS) Q9VB69 (/ISS) |
|
Malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473
Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
|
1 | Q9VG31 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
7 | Q2QBM1 (/IMP) Q9NIW0 (/IMP) Q9NIW1 (/IMP) Q9NIW2 (/IMP) Q9U1J1 (/IMP) Q9VG31 (/IMP) Q9VG32 (/IMP) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
7 | Q2QBM1 (/IMP) Q9NIW0 (/IMP) Q9NIW1 (/IMP) Q9NIW2 (/IMP) Q9U1J1 (/IMP) Q9VG31 (/IMP) Q9VG32 (/IMP) |
|
Regulation of cell death GO:0010941
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
7 | Q2QBM1 (/IMP) Q9NIW0 (/IMP) Q9NIW1 (/IMP) Q9NIW2 (/IMP) Q9U1J1 (/IMP) Q9VG31 (/IMP) Q9VG32 (/IMP) |
|
Sleep GO:0030431
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
|
7 | Q2QBM1 (/IMP) Q9NIW0 (/IMP) Q9NIW1 (/IMP) Q9NIW2 (/IMP) Q9U1J1 (/IMP) Q9VG31 (/IMP) Q9VG32 (/IMP) |
|
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
|
4 | E1JIZ4 (/ISS) E1JIZ5 (/ISS) Q9U1J0 (/ISS) Q9VB69 (/ISS) |
|
Malate metabolic process GO:0006108
The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
4 | E1JIZ4 (/ISS) E1JIZ5 (/ISS) Q9U1J0 (/ISS) Q9VB69 (/ISS) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
1 | E1JIZ4 (/IMP) |
|
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | Q9VG31 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | Q2QBM1 (/HDA) Q9NIW0 (/HDA) Q9NIW1 (/HDA) Q9NIW2 (/HDA) Q9U1J1 (/HDA) Q9VG31 (/HDA) Q9VG32 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | Q2QBM1 (/IDA) Q9NIW0 (/IDA) Q9NIW1 (/IDA) Q9NIW2 (/IDA) Q9U1J1 (/IDA) Q9VG31 (/IDA) Q9VG32 (/IDA) |
