The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"BRCT domain
".
FunFam 89: DDK kinase regulatory subunit DBF4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
|
1 | P32325 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P32325 (/IPI) |
|
Protein serine/threonine kinase activator activity GO:0043539
Binds to and increases the activity of a protein serine/threonine kinase.
|
1 | P32325 (/IGI) |
|
Protein serine/threonine kinase activator activity GO:0043539
Binds to and increases the activity of a protein serine/threonine kinase.
|
1 | P32325 (/IMP) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of exit from mitosis GO:0001100
Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
|
1 | P32325 (/IGI) |
|
Negative regulation of exit from mitosis GO:0001100
Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
|
1 | P32325 (/IMP) |
|
DNA replication initiation GO:0006270
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
|
1 | P32325 (/IPI) |
|
Premeiotic DNA replication GO:0006279
The replication of DNA that precedes meiotic cell division.
|
1 | P32325 (/IMP) |
|
Mitotic DNA replication checkpoint GO:0033314
A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
|
1 | P32325 (/IGI) |
|
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
1 | P32325 (/IDA) |
|
Positive regulation of meiosis I GO:0060903
Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
|
1 | P32325 (/IMP) |
|
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
|
1 | P32325 (/IGI) |
|
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
|
1 | P32325 (/IMP) |
|
Positive regulation of DNA replication initiation GO:1903468
Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
|
1 | P32325 (/IGI) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome, centromeric region GO:0000775
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
1 | P32325 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P32325 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P32325 (/HDA) |
|
Dbf4-dependent protein kinase complex GO:0031431
A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.
|
1 | P32325 (/IDA) |
|
Dbf4-dependent protein kinase complex GO:0031431
A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.
|
1 | P32325 (/IGI) |
|
Dbf4-dependent protein kinase complex GO:0031431
A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.
|
1 | P32325 (/IPI) |
