The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
5'-nuclease
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: 20S-pre-rRNA D-site endonuclease NOB1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
7 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q9FLL1 (/IDA)
Small ribosomal subunit rRNA binding GO:0070181
Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9UTK0 (/ISO)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
1 Q9UTK0 (/ISO)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
6 Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP)
Maturation of SSU-rRNA GO:0030490
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
6 Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI)
Proteasome assembly GO:0043248
The aggregation, arrangement and bonding together of a mature, active proteasome complex.
6 Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP) Q08444 (/IMP)
Proteasome assembly GO:0043248
The aggregation, arrangement and bonding together of a mature, active proteasome complex.
6 Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI) Q08444 (/IPI)
Cleavage involved in rRNA processing GO:0000469
Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
1 Q9FLL1 (/IDA)
Endonucleolytic cleavage involved in rRNA processing GO:0000478
Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.
1 Q9UTK0 (/ISO)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
1 Q9FLL1 (/IMP)
Embryo sac development GO:0009553
The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
1 Q9FLL1 (/IMP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
1 Q9FLL1 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q9UTK0 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q9FLL1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA) Q08444 (/HDA)
Preribosome, small subunit precursor GO:0030688
A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
6 Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA) Q08444 (/IDA)
Preribosome, small subunit precursor GO:0030688
A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
1 Q9UTK0 (/ISO)
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