The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 83: Sodium/potassium-transporting ATPase subunit alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium transmembrane transporter activity, phosphorylative mechanism GO:0005388
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
6 Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS)
Sodium:potassium-exchanging ATPase activity GO:0005391
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).
2 A0A060D574 (/IDA) A0A060D9G1 (/IDA)
Cation transmembrane transporter activity GO:0008324
Enables the transfer of cation from one side of a membrane to the other.
1 Q60CL1 (/ISS)
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
1 Q60CL1 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS) Q76NN8 (/TAS)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
6 Q76NN8 (/IDA) Q76NN8 (/IDA) Q76NN8 (/IDA) Q76NN8 (/IDA) Q76NN8 (/IDA) Q76NN8 (/IDA)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
2 G5EBE7 (/IMP) G5EC38 (/IMP)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
2 G5EBE7 (/IGI) G5EC38 (/IGI)
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 A0A060D574 (/IDA) A0A060D9G1 (/IDA)
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q60CL1 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 A0A060D574 (/IDA) A0A060D9G1 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 A0A060D9G1 (/IDA)
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