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CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 57: Copper-exporting P-type ATPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Silver ion transmembrane transporter activity GO:0015080
Enables the transfer of silver (Ag) ions from one side of a membrane to the other.
 15 Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP)
(5 more)
Ion transmembrane transporter activity, phosphorylative mechanism GO:0015662
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 2 O32220 (/IPI) O32220 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 15 Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP)
(5 more)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
 15 Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP)
(5 more)
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
 15 Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP)
(5 more)
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
 15 Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP)
(5 more)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 15 Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP)
(5 more)
Cellular response to silver ion GO:0071292
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 15 Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP) Q59385 (/IEP)
(5 more)
Silver ion transmembrane transport GO:1902601
The directed movement of silver ion across a membrane.
 15 Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP) Q59385 (/IMP)
(5 more)
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 5 Q9KPZ7 (/ISS) Q9KPZ7 (/ISS) Q9KPZ7 (/ISS) Q9KPZ7 (/ISS) Q9KPZ7 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 15 Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM) Q59385 (/ISM)
(5 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 15 Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA) Q59385 (/HDA)
(5 more)
Intrinsic component of membrane GO:0031224
The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
 15 Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA) Q59385 (/IDA)
(5 more)
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