The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 56: Cation-transporting ATPase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Manganese transmembrane transporter activity, phosphorylative mechanism GO:0015410
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).
2 Q9HD20 (/TAS) Q9HD20 (/TAS)
Ion transmembrane transporter activity, phosphorylative mechanism GO:0015662
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
1 Q9VKJ6 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
2 Q9HD20 (/TAS) Q9HD20 (/TAS)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
1 Q9VKJ6 (/ISS)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
1 Q9VKJ6 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
3 Q8MSI5 (/HDA) Q9VKJ6 (/HDA) Q9Y139 (/HDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q9HD20 (/TAS) Q9HD20 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q9HD20 (/HDA) Q9HD20 (/HDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q9VKJ6 (/ISS)
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