View in Gene3D

CATH Superfamily 3.40.50.1000

HAD superfamily/HAD-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: Sodium/potassium-transporting ATPase subunit alpha

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Na(+)/K(+)-exchanging ATPase. [EC: 7.2.2.13]
ATP + H(2)O + Na(+)(Side 1) + K(+)(Side 2) = ADP + phosphate + Na(+)(Side 2) + K(+)(Side 1).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37 and EC 3.6.3.9.
 109 A0A0D9S121 A0A0D9S121 A0A0D9S121 A0A0D9S121 A0A0D9S121 A0A0D9S121 A0A0S2Z3W6 A0A0S2Z3W6 A0A0S2Z3W6 A0A0S2Z3W6
(99 more...)
H(+)/K(+)-exchanging ATPase. [EC: 7.2.2.19]
ATP + H(2)O + H(+)[side 1] + K(+)[side 2] = ADP + phosphate + H(+)[side 2] + K(+)[side 1].
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • A gastric mucosal enzyme that catalyzes the efflux of one H(+) and the influx of one K(+) per ATP hydrolyzed.
  • Formerly EC 3.6.1.36 and EC 3.6.3.10.
 15 A0A384MR29 A0A384MR29 P09626 P19156 P20648 P20648 P27112 P50996 P54707 P54708
(5 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...