The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16: HAD family hydrolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
168 P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA)
(158 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
168 P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS)
(158 more)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
168 P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA)
(158 more)
5'-nucleotidase activity GO:0008253
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
168 P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS) P0AF25 (/ISS)
(158 more)
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
3 A4QFW4 (/IDA) A4QFW4 (/IDA) A4QFW4 (/IDA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
UMP catabolic process GO:0046050
The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.
168 P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP) P0AF24 (/IMP)
(158 more)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
3 A4QFW4 (/IMP) A4QFW4 (/IMP) A4QFW4 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
168 P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA) P0AF24 (/IDA)
(158 more)
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