The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HAD superfamily/HAD-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 123: glycerol-3-phosphate phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 A6NDG6 (/ISS) Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
3 A6NDG6 (/ISS) Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Glycerol-3-phosphatase activity GO:0043136
Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
3 Q2T9S4 (/ISS) Q2T9S4 (/ISS) Q5F4B1 (/ISS)
Nucleotide phosphatase activity, acting on free nucleotides GO:0098519
Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.
3 A6NDG6 (/ISS) Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Phosphoglycolate phosphatase activity GO:0008967
Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.
2 Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Glycerol-3-phosphatase activity GO:0043136
Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
2 A6NDG6 (/IDA) Q8CHP8 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q8CHP8 (/IDA)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
1 Q8CHP8 (/IDA)
Phosphoglycolate phosphatase activity GO:0008967
Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.
1 A6NDG6 (/IDA)
Phosphoglycolate phosphatase activity GO:0008967
Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.
1 Q8CHP8 (/ISO)
Glycerol-3-phosphatase activity GO:0043136
Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
1 D3ZDK7 (/IMP)
Glycerol-3-phosphatase activity GO:0043136
Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
1 Q8CHP8 (/ISO)
Nucleotide phosphatase activity, acting on free nucleotides GO:0098519
Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.
1 Q8CHP8 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
4 Q2T9S4 (/ISS) Q2T9S4 (/ISS) Q5F4B1 (/ISS) Q8CHP8 (/ISS)
Glycerol biosynthetic process GO:0006114
The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
3 A6NDG6 (/IDA) D3ZDK7 (/IDA) Q8CHP8 (/IDA)
Glycerol biosynthetic process GO:0006114
The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
3 Q2T9S4 (/ISS) Q2T9S4 (/ISS) Q5F4B1 (/ISS)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
3 Q2T9S4 (/ISS) Q2T9S4 (/ISS) Q5F4B1 (/ISS)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
3 A6NDG6 (/ISS) Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
3 A6NDG6 (/ISS) Q2T9S4 (/ISS) Q2T9S4 (/ISS)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
2 A6NDG6 (/IDA) Q8CHP8 (/IDA)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
2 A6NDG6 (/IMP) D3ZDK7 (/IMP)
Glycerol biosynthetic process GO:0006114
The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
1 Q8CHP8 (/ISO)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 D3ZDK7 (/IMP)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 Q8CHP8 (/ISO)
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
1 Q8CHP8 (/IDA)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
1 Q8CHP8 (/IDA)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
1 Q8CHP8 (/ISO)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 D3ZDK7 (/TAS)
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