The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3: Fatty acid synthase subunit beta dehydratase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid synthase activity GO:0004312
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
1 Q9UUG0 (/IDA)
Fatty acid synthase activity GO:0004312
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
1 Q5AV07 (/RCA)
[acyl-carrier-protein] S-acetyltransferase activity GO:0004313
Catalysis of the reaction: acetyl-CoA +
1 Q9UUG0 (/ISO)
[acyl-carrier-protein] S-acetyltransferase activity GO:0004313
Catalysis of the reaction: acetyl-CoA +
1 Q5A4W7 (/ISS)
[acyl-carrier-protein] S-acetyltransferase activity GO:0004313
Catalysis of the reaction: acetyl-CoA +
1 Q5AV07 (/RCA)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q9UUG0 (/ISO)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q5A4W7 (/ISS)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q5AV07 (/RCA)
3-oxoacyl-[acyl-carrier-protein] synthase activity GO:0004315
Catalysis of the reaction: acyl-
1 Q5AV07 (/RCA)
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
1 Q5AV07 (/RCA)
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity GO:0004317
Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-
1 Q9UUG0 (/ISO)
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity GO:0004317
Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-
1 Q5A4W7 (/ISS)
3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity GO:0004317
Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-
1 Q5AV07 (/RCA)
Enoyl-[acyl-carrier-protein] reductase (NADH) activity GO:0004318
Catalysis of the reaction: acyl-
1 Q9UUG0 (/ISO)
Enoyl-[acyl-carrier-protein] reductase (NADH) activity GO:0004318
Catalysis of the reaction: acyl-
1 Q5A4W7 (/ISS)
Enoyl-[acyl-carrier-protein] reductase (NADH) activity GO:0004318
Catalysis of the reaction: acyl-
1 Q5AV07 (/RCA)
Oleoyl-[acyl-carrier-protein] hydrolase activity GO:0004320
Catalysis of the reaction: oleoyl-
1 Q5AV07 (/RCA)
Fatty-acyl-CoA synthase activity GO:0004321
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
1 Q9UUG0 (/NAS)
Fatty-acyl-CoA synthase activity GO:0004321
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
1 Q5AV07 (/RCA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q9UUG0 (/IDA)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q5A4W7 (/ISS)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q5AV07 (/RCA)
Secondary metabolic process GO:0019748
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
1 Q00706 (/RCA)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q5A4W7 (/IMP)
Sterigmatocystin biosynthetic process GO:0045461
The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
1 Q00706 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UUG0 (/HDA)
Fatty acid synthase complex GO:0005835
A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.
1 Q9UUG0 (/IDA)
Fatty acid synthase complex GO:0005835
A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.
1 Q5A4W7 (/ISS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...