The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Malonyl CoA-acyl carrier protein transacylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
115 P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP) P0AAI9 (/IMP)
(105 more)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
6 Q8T3L6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q8IVS2 (/HDA)
Fatty acid synthase activity GO:0004312
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
1 Q8IVS2 (/IDA)
Fatty acid synthase activity GO:0004312
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
1 Q8R3F5 (/ISO)
Fatty acid synthase activity GO:0004312
Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
1 Q8T3L6 (/ISS)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q8IVS2 (/IDA)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q8R3F5 (/ISO)
[acyl-carrier-protein] S-malonyltransferase activity GO:0004314
Catalysis of the reaction: malonyl-CoA +
1 Q8IVS2 (/TAS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
120 G3XCZ6 (/IDA) G3XCZ6 (/IDA) O54437 (/IDA) O54437 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA)
(110 more)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
6 Q8T3L6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS) Q9KQH6 (/ISS)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q8R3F5 (/ISO)
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
1 Q8IVS2 (/TAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
115 P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA) P0AAI9 (/IDA)
(105 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8IVS2 (/IDA) Q8RU07 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R3F5 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8R3F5 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8T3L6 (/ISS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q8IVS2 (/TAS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q8RU07 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 Q8RU07 (/IDA)
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