The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Aldehyde Dehydrogenase; Chain A, domain 2
".
FunFam 10: Gamma-aminobutyraldehyde dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
27 |
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
(17 more) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
18 |
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
(8 more) |
Aminobutyraldehyde dehydrogenase activity GO:0019145
Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.
|
5 | P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) |
1-pyrroline dehydrogenase activity GO:0033737
Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
|
5 | P77674 (/IMP) P77674 (/IMP) P77674 (/IMP) P77674 (/IMP) P77674 (/IMP) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
5 | P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) |
Vanillin dehydrogenase activity GO:0050608
Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.
|
2 | G2IMC6 (/IMP) G2IMC6 (/IMP) |
Aldehyde dehydrogenase [NAD(P)+] activity GO:0004030
Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
|
1 | Q8GAK7 (/IDA) |
Vanillin dehydrogenase activity GO:0050608
Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.
|
1 | O05619 (/IDA) |
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
1 | Q8GAK7 (/IDA) |
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
1 | Q8GAK7 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Putrescine catabolic process GO:0009447
The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.
|
23 |
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
(13 more) |
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
|
18 |
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
(8 more) |
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
|
18 |
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
P76149 (/IDA)
(8 more) |
Putrescine catabolic process GO:0009447
The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.
|
18 |
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
(8 more) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
18 |
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
P76149 (/IEP)
(8 more) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
18 |
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
P76149 (/IMP)
(8 more) |
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
9 | P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) P9WNX9 (/IDA) |
D-xylose catabolic process GO:0042843
The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.
|
1 | Q8GAK7 (/TAS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) P9WNX9 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) P77674 (/IDA) |