The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 104: Thioredoxin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 13 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor GO:0016671
Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
|
15 |
P29448 (/IDA)
P29448 (/IDA)
P29448 (/IDA)
Q0D840 (/IDA)
Q0D840 (/IDA)
Q0D840 (/IDA)
Q0D840 (/IDA)
Q0D840 (/IDA)
Q0D840 (/IDA)
Q38879 (/IDA)
(5 more) |
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
10 | P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) Q9V429 (/IDA) |
Disulfide oxidoreductase activity GO:0015036
Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
|
9 | P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) P22803 (/ISS) Q8IFW4 (/ISS) |
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
|
6 | Q0D840 (/IDA) Q0D840 (/IDA) Q0D840 (/IDA) Q0D840 (/IDA) Q0D840 (/IDA) Q0D840 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O14463 (/IPI) P29448 (/IPI) P29448 (/IPI) P29448 (/IPI) Q42403 (/IPI) Q42403 (/IPI) |
Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor GO:0016671
Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
|
6 | Q0D840 (/TAS) Q0D840 (/TAS) Q0D840 (/TAS) Q0D840 (/TAS) Q0D840 (/TAS) Q0D840 (/TAS) |
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
|
3 | P29448 (/IDA) P29448 (/IDA) P29448 (/IDA) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
3 | A0A1D8PU69 (/IMP) A0A1D8PU69 (/IMP) O14463 (/IMP) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | O14463 (/EXP) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | O14463 (/IDA) |
Showing 1 to 10 of 13 entries
There are 38 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Vacuole inheritance GO:0000011
The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
|
17 |
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22217 (/IMP)
P22803 (/IMP)
(7 more) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
17 |
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22803 (/IDA)
(7 more) |
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890
The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
|
17 |
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22803 (/IDA)
(7 more) |
Vacuole fusion, non-autophagic GO:0042144
The fusion of two vacuole membranes to form a single vacuole.
|
17 |
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22803 (/IDA)
(7 more) |
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
17 |
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22803 (/IGI)
(7 more) |
Protein deglutathionylation GO:0080058
The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.
|
17 |
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22803 (/IDA)
(7 more) |
Protein deglutathionylation GO:0080058
The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.
|
17 |
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22217 (/IGI)
P22803 (/IGI)
(7 more) |
Sulfate assimilation GO:0000103
The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
|
8 | P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) |
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
|
8 | P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) P22803 (/IGI) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
8 | Q0D840 (/IEP) Q0D840 (/IEP) Q0D840 (/IEP) Q0D840 (/IEP) Q0D840 (/IEP) Q0D840 (/IEP) Q39241 (/IEP) Q39241 (/IEP) |
Showing 1 to 10 of 38 entries
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
40 |
A0A1D8PU69 (/IDA)
A0A1D8PU69 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
P22217 (/IDA)
(30 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | O14463 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | O14463 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) |
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
|
9 | P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) P22217 (/IPI) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
9 | P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) P22217 (/HDA) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
9 | P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) P22217 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | P29448 (/TAS) P29448 (/TAS) P29448 (/TAS) Q38879 (/TAS) Q39239 (/TAS) Q39241 (/TAS) Q39241 (/TAS) Q42403 (/TAS) Q42403 (/TAS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | Q38879 (/IDA) Q39241 (/IDA) Q39241 (/IDA) Q42403 (/IDA) Q42403 (/IDA) |
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
|
5 | P29448 (/IDA) P29448 (/IDA) P29448 (/IDA) Q39241 (/IDA) Q39241 (/IDA) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
4 | Q39241 (/IDA) Q39241 (/IDA) Q42403 (/IDA) Q42403 (/IDA) |
Showing 1 to 10 of 21 entries