The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Dimethylsulfoxide Reductase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Formate dehydrogenase, alpha subunit, selenocystei...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P24183 (/IPI) P32176 (/IPI) P32176 (/IPI) P32176 (/IPI) P32176 (/IPI)
Formate dehydrogenase (quinone) activity GO:0036397
Catalysis of the reaction: formate + a quinone = CO2 + a quinol.
5 P24183 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA)
Formate dehydrogenase (NAD+) activity GO:0008863
Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.
3 Q609M3 (/ISS) Q74F32 (/ISS) Q8EKJ1 (/ISS)
Formate dehydrogenase (cytochrome-c-553) activity GO:0047111
Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.
2 Q727P3 (/IDA) Q727P3 (/IDA)
Selenium binding GO:0008430
Interacting selectively and non-covalently with selenium (Se).
1 P24183 (/IDA)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
1 P24183 (/IDA)
Molybdenum ion binding GO:0030151
Interacting selectively and non-covalently with molybdenum (Mo) ions.
1 P24183 (/IDA)
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
1 P24183 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formate oxidation GO:0015944
The chemical reactions and pathways by which formate is converted to CO2.
5 P24183 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
4 P32176 (/IEP) P32176 (/IEP) P32176 (/IEP) P32176 (/IEP)
Cellular respiration GO:0045333
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
4 P32176 (/IEP) P32176 (/IEP) P32176 (/IEP) P32176 (/IEP)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
3 Q609M3 (/ISS) Q74F32 (/ISS) Q8EKJ1 (/ISS)
Molybdenum incorporation into iron-sulfur cluster GO:0018291
The incorporation of molybdenum into an iron-sulfur cluster.
2 Q727P3 (/IDA) Q727P3 (/IDA)
Anaerobic respiration GO:0009061
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
1 P24183 (/IEP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 Q609M3 (/ISS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formate dehydrogenase complex GO:0009326
An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).
7 P24183 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA) Q727P3 (/IDA) Q727P3 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 P24183 (/HDA) P32176 (/HDA) P32176 (/HDA) P32176 (/HDA) P32176 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P32176 (/IDA) P32176 (/IDA) P32176 (/IDA) P32176 (/IDA)
Formate dehydrogenase complex GO:0009326
An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).
3 Q609M3 (/ISS) Q74F32 (/ISS) Q8EKJ1 (/ISS)
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
2 Q727P3 (/IDA) Q727P3 (/IDA)
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
1 P24183 (/IDA)
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