The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Nsp3, SUD-M subdomain
".
FunFam 2: Polyprotein ORF1ab
There are 5 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
SARS coronavirus main proteinase.
[EC: 3.4.22.69]
TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
|
5 | K9N638 K9N638 K9N7C7 M1RUQ1 M1RUQ1 |
|
Ubiquitinyl hydrolase 1.
[EC: 3.4.19.12]
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
|
5 | K9N638 K9N638 K9N7C7 M1RUQ1 M1RUQ1 |
|
RNA helicase.
[EC: 3.6.4.13]
ATP + H(2)O = ADP + phosphate.
|
1 | K9N7C7 |
|
DNA helicase.
[EC: 3.6.4.12]
ATP + H(2)O = ADP + phosphate.
|
1 | K9N7C7 |
|
RNA-directed RNA polymerase.
[EC: 2.7.7.48]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
|
1 | K9N7C7 |
