The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Severin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25: Actin-depolymerizing factor 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q39251 (/IPI) Q39251 (/IPI) Q9ZSK4 (/IPI) Q9ZSK4 (/IPI)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q8LFH6 (/IDA) Q8LFH6 (/IDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 B9TRQ1 (/ISM)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 A8MR09 (/TAS)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 B9TRQ1 (/ISM)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin filament depolymerization GO:0030042
Disassembly of actin filaments by the removal of actin monomers from a filament.
15 A8MR09 (/IDA) Q39251 (/IDA) Q39251 (/IDA) Q570Y6 (/IDA) Q570Y6 (/IDA) Q67ZM4 (/IDA) Q8LFH6 (/IDA) Q8LFH6 (/IDA) Q9LQ81 (/IDA) Q9LQ81 (/IDA)
(5 more)
Petal development GO:0048441
The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
4 A1XJ49 (/IEP) A1XJ49 (/IEP) Q4JHK7 (/IEP) Q4JHK7 (/IEP)
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
4 O49606 (/IDA) O49606 (/IDA) Q9ZNT3 (/IDA) Q9ZNT3 (/IDA)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
4 A1XJ46 (/IEP) A1XJ46 (/IEP) Q208T5 (/IEP) Q208T5 (/IEP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
2 Q8LFH6 (/IMP) Q8LFH6 (/IMP)
Defense response signaling pathway, resistance gene-dependent GO:0009870
A series of molecular signals that depends upon R-genes and is activated during defense response.
2 Q9ZSK3 (/IMP) Q9ZSK3 (/IMP)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 A1XJ44 (/IDA) A1XJ44 (/IDA)
Actin filament polymerization GO:0030041
Assembly of actin filaments by the addition of actin monomers to a filament.
2 O49606 (/IDA) O49606 (/IDA)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
2 Q9ZSK3 (/IMP) Q9ZSK3 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9ZSK4 (/IEP) Q9ZSK4 (/IEP)
Anther development GO:0048653
The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.
2 A1XJ44 (/IEP) A1XJ44 (/IEP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 A8MR09 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 Q39251 (/IDA) Q39251 (/IDA) Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Actin filament GO:0005884
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
3 Q67ZM4 (/IDA) Q8LFH6 (/IDA) Q8LFH6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q39251 (/IDA) Q39251 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q39251 (/IDA) Q39251 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
2 Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9ZSK4 (/IDA) Q9ZSK4 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
2 Q8LFH6 (/IDA) Q8LFH6 (/IDA)
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