The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Severin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 168: Actin-depolymerizing factor 1, isoforms a/b

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
1 Q07750 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 Q07750 (/IMP)
Actin filament depolymerization GO:0030042
Disassembly of actin filaments by the removal of actin monomers from a filament.
1 Q07750 (/IDA)
Actin filament depolymerization GO:0030042
Disassembly of actin filaments by the removal of actin monomers from a filament.
1 Q07750 (/IMP)
Skeletal muscle thin filament assembly GO:0030240
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.
1 Q07750 (/IMP)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
1 Q07750 (/IDA)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
1 Q07750 (/IGI)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
1 Q07750 (/IMP)
Actin filament severing GO:0051014
The process in which an actin filament is broken down into smaller filaments.
1 Q07750 (/IDA)
Muscle thin filament assembly GO:0071689
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
1 Q07750 (/IGI)
Muscle thin filament assembly GO:0071689
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
1 Q07750 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q07750 (/IDA)
Striated muscle thin filament GO:0005865
Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
1 Q07750 (/IDA)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q07750 (/IPI)
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