The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Periplasmic binding protein-like II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 54: Glutamate receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
7 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
7 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 O81078 (/IPI) Q8GXJ4 (/IPI) Q8GXJ4 (/IPI) Q9LV72 (/IPI)
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
3 Q8GXJ4 (/IMP) Q8GXJ4 (/IMP) Q9C8E7 (/IMP)
Glutamate receptor activity GO:0008066
Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
3 Q8GXJ4 (/IMP) Q8GXJ4 (/IMP) Q9C8E7 (/IMP)
Ligand-gated ion channel activity GO:0015276
Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
2 Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
1 F4ITQ0 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
8 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9C8E7 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
7 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
7 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q8GXJ4 (/IMP) Q8GXJ4 (/IMP) Q9C8E7 (/IMP)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
3 Q8GXJ4 (/IMP) Q8GXJ4 (/IMP) Q9C8E7 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
2 Q84W41 (/IMP) Q9C8E7 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 Q8GXJ4 (/IEP) Q8GXJ4 (/IEP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 Q84W41 (/IMP) Q9C8E7 (/IMP)
Induced systemic resistance, jasmonic acid mediated signaling pathway GO:0009864
The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.
2 Q84W41 (/IMP) Q9C8E7 (/IMP)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
2 Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
2 Q8GXJ4 (/IEP) Q8GXJ4 (/IEP)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
2 Q8GXJ4 (/IEP) Q8GXJ4 (/IEP)
Cellular response to acetate GO:0071311
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.
2 Q8GXJ4 (/IEP) Q8GXJ4 (/IEP)
Gravitropism GO:0009630
The orientation of plant parts under the stimulation of gravity.
1 Q9C8E7 (/IMP)
Seed germination GO:0009845
The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
1 F4ITQ0 (/IMP)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
1 Q9C8E7 (/IMP)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
1 Q9C8E7 (/IMP)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
1 F4ITQ0 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 O81078 (/ISS) Q7XJL2 (/ISS) Q84W41 (/ISS) Q93YT1 (/ISS) Q9C8E7 (/ISS) Q9FH75 (/ISS) Q9LV72 (/ISS) Q9SW97 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 F4ITQ0 (/IDA) Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
2 Q8GXJ4 (/IDA) Q8GXJ4 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 F4ITQ0 (/IDA)
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