The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Periplasmic binding protein-like II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: DNA-binding transcriptional regulator OxyR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial-type proximal promoter sequence-specific DNA binding GO:0000986
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a bacterial gene (or cistron, or operon). The proximal promoter is in cis with and relatively close to the core promoter.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
9 Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
5 M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
5 M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
130 P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP) P0ACQ4 (/IEP)
(120 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
Regulation of DNA-templated transcription, initiation GO:2000142
Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
9 Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS) Q9KNU4 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 M4U7P6 (/IEP) M4U7P6 (/IEP) M4U7P6 (/IEP) M4U7P6 (/IEP) M4U7P6 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
130 P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA) P0ACQ4 (/IDA)
(120 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
5 M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA) M4U7P6 (/IDA)
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