The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Periplasmic binding protein-like II
".
FunFam 170: Glutamate receptor ionotropic, NMDA 2D
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
NMDA glutamate receptor activity GO:0004972
An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.
|
4 | O76903 (/ISS) Q6IWN7 (/ISS) Q9W581 (/ISS) X2JDW0 (/ISS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
4 | O76903 (/IGI) Q6IWN7 (/IGI) Q9W581 (/IGI) X2JDW0 (/IGI) |
|
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
4 | O76903 (/IMP) Q6IWN7 (/IMP) Q9W581 (/IMP) X2JDW0 (/IMP) |
|
Ionotropic glutamate receptor signaling pathway GO:0035235
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
|
4 | O76903 (/IDA) Q6IWN7 (/IDA) Q9W581 (/IDA) X2JDW0 (/IDA) |
|
Sensory perception of touch GO:0050975
The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).
|
4 | O76903 (/IMP) Q6IWN7 (/IMP) Q9W581 (/IMP) X2JDW0 (/IMP) |
|
Medium-term memory GO:0072375
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
|
4 | O76903 (/IMP) Q6IWN7 (/IMP) Q9W581 (/IMP) X2JDW0 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ionotropic glutamate receptor complex GO:0008328
A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
|
4 | O76903 (/IPI) Q6IWN7 (/IPI) Q9W581 (/IPI) X2JDW0 (/IPI) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | O76903 (/IDA) Q6IWN7 (/IDA) Q9W581 (/IDA) X2JDW0 (/IDA) |
