The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Transcription factor, MADS-box
".
FunFam 1: Myocyte-specific enhancer factor 2A homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 61 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
103 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(93 more) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
61 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(51 more) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(44 more) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
53 |
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(43 more) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
53 |
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(43 more) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
34 |
O55087 (/IDA)
P40791 (/IDA)
Q02078 (/IDA)
Q02078 (/IDA)
Q02080 (/IDA)
Q02080 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(24 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
34 |
A0A096MJY4 (/IPI)
O89038 (/IPI)
P40791 (/IPI)
Q02078 (/IPI)
Q02078 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
(24 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
32 |
A0A096MJY4 (/IDA)
Q02078 (/IDA)
Q02078 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(22 more) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
31 |
O55087 (/IDA)
Q02078 (/IDA)
Q02078 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(21 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
30 |
Q02078 (/ISA)
Q02078 (/ISA)
Q02080 (/ISA)
Q02080 (/ISA)
Q06413 (/ISA)
Q06413 (/ISA)
Q06413 (/ISA)
Q06413 (/ISA)
Q06413 (/ISA)
Q06413 (/ISA)
(20 more) |
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
29 |
Q02078 (/IDA)
Q02078 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(19 more) |
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
|
29 |
Q02078 (/IPI)
Q02078 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
(19 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
28 |
Q02078 (/ISM)
Q02078 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
Q06413 (/ISM)
(18 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
28 |
Q02078 (/NAS)
Q02078 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
(18 more) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
28 |
Q02078 (/IPI)
Q02078 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
Q06413 (/IPI)
(18 more) |
AT DNA binding GO:0003680
Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
24 |
A0A068EUV3 (/IDA)
A0A068F1F8 (/IDA)
A0A0R4IRM3 (/IDA)
A0A0U3JVR0 (/IDA)
A0A0U3L6K5 (/IDA)
A0A2R8QIE4 (/IDA)
A0A2R8QMZ5 (/IDA)
A0A2R8QU09 (/IDA)
E9QCL1 (/IDA)
F1Q910 (/IDA)
(14 more) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
8 | Q02078 (/IDA) Q02078 (/IDA) Q03414 (/IDA) Q2MJT0 (/IDA) Q60929 (/IDA) Q8CFN5 (/IDA) Q9PSD8 (/IDA) Q9U325 (/IDA) |
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
7 | Q02078 (/IDA) Q02078 (/IDA) Q02080 (/IDA) Q02080 (/IDA) Q60929 (/IDA) Q63943 (/IDA) Q8CFN5 (/IDA) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) Q9W6U8 (/ISS) |
Histone acetyltransferase binding GO:0035035
Interacting selectively and non-covalently with the enzyme histone acetyltransferase.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) Q60929 (/ISS) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) Q60929 (/ISS) |
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) Q60929 (/ISS) |
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
|
6 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
6 | Q02078 (/IPI) Q02078 (/IPI) Q02080 (/IPI) Q02080 (/IPI) Q14814 (/IPI) Q8CFN5 (/IPI) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
5 | A0A096MJY4 (/IDA) P40791 (/IDA) Q60929 (/IDA) Q63943 (/IDA) Q8CFN5 (/IDA) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
4 | Q02078 (/IDA) Q02078 (/IDA) Q60929 (/IDA) Q8CFN5 (/IDA) |
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
3 | Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | O55087 (/IMP) P40791 (/IMP) Q8CFN5 (/IMP) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | O55087 (/ISO) Q60929 (/ISO) Q8CFN5 (/ISO) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
3 | Q02080 (/NAS) Q02080 (/NAS) Q14814 (/NAS) |
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
|
3 | Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
3 | O55087 (/ISO) Q60929 (/ISO) Q63943 (/ISO) |
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | O55087 (/ISO) Q60929 (/ISO) |
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
|
2 | O55087 (/IDA) Q8CFN5 (/IDA) |
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
2 | Q02078 (/IPI) Q02078 (/IPI) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q60929 (/ISO) Q8CFN5 (/ISO) |
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
2 | Q02078 (/IDA) Q02078 (/IDA) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | Q03414 (/IPI) Q60929 (/IPI) |
Histone acetyltransferase binding GO:0035035
Interacting selectively and non-covalently with the enzyme histone acetyltransferase.
|
2 | Q02078 (/IPI) Q02078 (/IPI) |
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
2 | O55087 (/IDA) Q63943 (/IDA) |
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
2 | Q02078 (/IPI) Q02078 (/IPI) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q60929 (/ISO) Q8CFN5 (/ISO) |
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
|
1 | Q8CFN5 (/IDA) |
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
1 | Q60929 (/ISO) |
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | P40791 (/IDA) |
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q60929 (/IC) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q8CFN5 (/ISO) |
AT DNA binding GO:0003680
Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
|
1 | Q8CFN5 (/ISO) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q60929 (/ISO) |
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q60929 (/ISO) |
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q63943 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9PSD8 (/ISS) |
Histone acetyltransferase binding GO:0035035
Interacting selectively and non-covalently with the enzyme histone acetyltransferase.
|
1 | Q60929 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q63943 (/IPI) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q60929 (/ISO) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | Q8CFN5 (/IDA) |
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
1 | Q60929 (/ISO) |
HMG box domain binding GO:0071837
Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.
|
1 | Q8CFN5 (/IPI) |
There are 270 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
85 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(75 more) |
B cell homeostasis GO:0001782
The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Germinal center formation GO:0002467
The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Cellular response to trichostatin A GO:0035984
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Regulation of megakaryocyte differentiation GO:0045652
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Renal tubule morphogenesis GO:0061333
The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Cellular response to fluid shear stress GO:0071498
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Glomerulus morphogenesis GO:0072102
The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Nephron tubule epithelial cell differentiation GO:0072160
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013
Any epithelial cell proliferation that is involved in renal tubule morphogenesis.
|
79 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(69 more) |
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Regulation of germinal center formation GO:0002634
Any process that modulates the frequency, rate, or extent of germinal center formation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Primary heart field specification GO:0003138
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Sinoatrial valve morphogenesis GO:0003185
The process in which the structure of the sinoatrial valve is generated and organized.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of alkaline phosphatase activity GO:0010694
Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Neural crest cell differentiation GO:0014033
The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Melanocyte differentiation GO:0030318
The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of bone mineralization GO:0030501
Any process that activates or increases the frequency, rate or extent of bone mineralization.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Ventricular cardiac muscle cell differentiation GO:0055012
The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of cardiac muscle cell proliferation GO:0060045
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of macrophage apoptotic process GO:2000111
Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of cardiac muscle cell differentiation GO:2000727
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Positive regulation of behavioral fear response GO:2000987
Any process that activates or increases the frequency, rate or extent of behavioral fear response.
|
72 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(62 more) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Blood vessel remodeling GO:0001974
The reorganization or renovation of existing blood vessels.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Chondrocyte differentiation GO:0002062
The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Cardiac ventricle formation GO:0003211
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Muscle cell fate determination GO:0007521
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Smooth muscle cell differentiation GO:0051145
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Positive regulation of protein homodimerization activity GO:0090073
Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
|
71 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(61 more) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
62 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(52 more) |
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
61 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(51 more) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
61 |
A0A096MJY4 (/ISS)
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(51 more) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
59 |
A0A068EUV3 (/IDA)
A0A068F1F8 (/IDA)
A0A0R4IRM3 (/IDA)
A0A0U3JVR0 (/IDA)
A0A0U3L6K5 (/IDA)
A0A2R8QIE4 (/IDA)
A0A2R8QMZ5 (/IDA)
A0A2R8QU09 (/IDA)
E9QCL1 (/IDA)
F1Q910 (/IDA)
(49 more) |
Negative regulation of ossification GO:0030279
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Positive regulation of skeletal muscle tissue development GO:0048643
Any process that activates, maintains or increases the rate of skeletal muscle tissue development.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Cellular response to parathyroid hormone stimulus GO:0071374
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(44 more) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(44 more) |
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(44 more) |
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(44 more) |
Regulation of synaptic activity GO:0060025
Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(44 more) |
Positive regulation of skeletal muscle cell differentiation GO:2001016
Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
|
54 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(44 more) |
Cardiocyte differentiation GO:0035051
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
|
46 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(36 more) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
46 |
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(36 more) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
32 |
A0A096MJY4 (/IMP)
O55087 (/IMP)
P40791 (/IMP)
Q03414 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
(22 more) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
29 |
O55087 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(19 more) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
29 |
A0A096MJY4 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(19 more) |
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
28 |
Q02078 (/IDA)
Q02078 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(18 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
28 |
A0A096MJY4 (/IEP)
Q02078 (/IEP)
Q02078 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
(18 more) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
28 |
Q02080 (/TAS)
Q02080 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
(18 more) |
Positive regulation of muscle cell differentiation GO:0051149
Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.
|
27 |
Q02078 (/TAS)
Q02078 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
(17 more) |
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
26 |
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
(16 more) |
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
26 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(16 more) |
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Cell morphogenesis involved in neuron differentiation GO:0048667
The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Regulation of dendritic spine development GO:0060998
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
26 |
A0A096MJY4 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(16 more) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
25 |
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
(15 more) |
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
25 |
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
(15 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
25 |
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
Q06413 (/NAS)
(15 more) |
Myotube differentiation GO:0014902
The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
|
25 |
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
(15 more) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
25 |
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
Q06413 (/IEP)
(15 more) |
Negative regulation of ossification GO:0030279
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Negative regulation of blood vessel endothelial cell migration GO:0043537
Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
25 |
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
(15 more) |
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
25 |
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
(15 more) |
Positive regulation of skeletal muscle tissue development GO:0048643
Any process that activates, maintains or increases the rate of skeletal muscle tissue development.
|
25 |
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
Q06413 (/IMP)
(15 more) |
Regulation of synapse assembly GO:0051963
Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
25 |
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(15 more) |
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
25 |
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
Q06413 (/ISS)
(15 more) |
Cellular response to parathyroid hormone stimulus GO:0071374
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Negative regulation of vascular smooth muscle cell proliferation GO:1904706
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Negative regulation of vascular smooth muscle cell proliferation GO:1904706
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
25 |
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
(15 more) |
Negative regulation of vascular associated smooth muscle cell migration GO:1904753
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Negative regulation of vascular associated smooth muscle cell migration GO:1904753
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
25 |
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
(15 more) |
Negative regulation of vascular endothelial cell proliferation GO:1905563
Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.
|
25 |
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
Q06413 (/IGI)
(15 more) |
Positive regulation of cardiac muscle cell differentiation GO:2000727
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Positive regulation of skeletal muscle cell differentiation GO:2001016
Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Heart formation GO:0060914
The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.
|
22 |
A0A068EUV3 (/IGI)
A0A068F1F8 (/IGI)
A0A076GH28 (/IGI)
A0A0R4ITE5 (/IGI)
A0A0U3JR38 (/IGI)
A0A0U3JVR0 (/IGI)
A0A0U3L6K5 (/IGI)
A0A2R8QP40 (/IGI)
A0A2R8RQE8 (/IGI)
A2BGA7 (/IGI)
(12 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
19 |
A0A076GH28 (/IMP)
A0A0R4IRM3 (/IMP)
A0A0R4ITE5 (/IMP)
A0A0U3JR38 (/IMP)
A0A2R8QIE4 (/IMP)
A0A2R8QMZ5 (/IMP)
A0A2R8QP40 (/IMP)
A0A2R8QU09 (/IMP)
A0A2R8RQE8 (/IMP)
A2BGA7 (/IMP)
(9 more) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
18 |
A0A068EUV3 (/IDA)
A0A068F1F8 (/IDA)
A0A076GH28 (/IDA)
A0A0R4ITE5 (/IDA)
A0A0U3JR38 (/IDA)
A0A0U3JVR0 (/IDA)
A0A0U3L6K5 (/IDA)
A0A2R8QP40 (/IDA)
A0A2R8RQE8 (/IDA)
A2BGA7 (/IDA)
(8 more) |
Cardiac muscle cell differentiation GO:0055007
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
|
17 |
A0A068EUV3 (/IGI)
A0A068F1F8 (/IGI)
A0A076GH28 (/IGI)
A0A0R4ITE5 (/IGI)
A0A0U3JR38 (/IGI)
A0A0U3JVR0 (/IGI)
A0A0U3L6K5 (/IGI)
A0A2R8QP40 (/IGI)
A0A2R8RQE8 (/IGI)
A2BGA7 (/IGI)
(7 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
16 |
A0A068EUV3 (/IGI)
A0A068F1F8 (/IGI)
A0A076GH28 (/IGI)
A0A0R4ITE5 (/IGI)
A0A0U3JR38 (/IGI)
A0A0U3JVR0 (/IGI)
A0A0U3L6K5 (/IGI)
A0A2R8QP40 (/IGI)
A0A2R8RQE8 (/IGI)
A2BGA7 (/IGI)
(6 more) |
Cardiac muscle cell development GO:0055013
The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.
|
16 |
A0A068EUV3 (/IGI)
A0A068F1F8 (/IGI)
A0A076GH28 (/IGI)
A0A0R4ITE5 (/IGI)
A0A0U3JR38 (/IGI)
A0A0U3JVR0 (/IGI)
A0A0U3L6K5 (/IGI)
A0A2R8QP40 (/IGI)
A0A2R8RQE8 (/IGI)
A2BGA7 (/IGI)
(6 more) |
Skeletal muscle myosin thick filament assembly GO:0030241
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.
|
14 |
A0A068EUV3 (/IGI)
A0A068F1F8 (/IGI)
A0A0U3JVR0 (/IGI)
A0A0U3L6K5 (/IGI)
E9QCL1 (/IGI)
F1Q910 (/IGI)
F1QE20 (/IGI)
F8W591 (/IGI)
F8W591 (/IGI)
Q4G0B4 (/IGI)
(4 more) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
11 |
A0A0R4IRM3 (/IMP)
A0A2R8QIE4 (/IMP)
A0A2R8QMZ5 (/IMP)
A0A2R8QU09 (/IMP)
Q1LXH3 (/IMP)
Q1LXH4 (/IMP)
Q1LXH5 (/IMP)
Q1LXH6 (/IMP)
Q2MJS9 (/IMP)
Q8CFN5 (/IMP)
(1 more) |
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
10 | A0A0R4IRM3 (/IMP) A0A2R8QIE4 (/IMP) A0A2R8QMZ5 (/IMP) A0A2R8QU09 (/IMP) Q1LXH3 (/IMP) Q1LXH4 (/IMP) Q1LXH5 (/IMP) Q1LXH6 (/IMP) Q2MJS9 (/IMP) Q98868 (/IMP) |
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
|
10 | A0A0R4IRM3 (/IMP) A0A2R8QIE4 (/IMP) A0A2R8QMZ5 (/IMP) A0A2R8QU09 (/IMP) Q1LXH3 (/IMP) Q1LXH4 (/IMP) Q1LXH5 (/IMP) Q1LXH6 (/IMP) Q2MJS9 (/IMP) Q98868 (/IMP) |
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
|
9 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q8CFN5 (/IMP) Q98869 (/IMP) |
Embryonic heart tube morphogenesis GO:0003143
The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
|
8 | A0A076GH28 (/IMP) A0A0R4ITE5 (/IMP) A0A0U3JR38 (/IMP) A0A2R8QP40 (/IMP) A0A2R8RQE8 (/IMP) A2BGA7 (/IMP) B5A8L9 (/IMP) F1QNL1 (/IMP) |
Ligamentous ossification GO:0036076
Ossification wherein bone tissue forms within ligamentous tissue.
|
8 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q98869 (/IMP) |
Regulation of osteoblast differentiation GO:0045667
Any process that modulates the frequency, rate or extent of osteoblast differentiation.
|
8 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q98869 (/IMP) |
Cardiac muscle cell differentiation GO:0055007
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
|
8 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q98869 (/IMP) |
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
|
8 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q98869 (/IMP) |
Heart formation GO:0060914
The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.
|
8 | A0A068EUV3 (/IMP) A0A068F1F8 (/IMP) A0A0U3JVR0 (/IMP) A0A0U3L6K5 (/IMP) E9QCL1 (/IMP) Q6NSN7 (/IMP) Q6PCS3 (/IMP) Q98869 (/IMP) |
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q02078 (/ISS) Q02078 (/ISS) Q5REW7 (/ISS) |
Mitochondrion distribution GO:0048311
Any process that establishes the spatial arrangement of mitochondria between and within cells.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q02078 (/ISS) Q02078 (/ISS) Q5REW7 (/ISS) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q02078 (/ISS) Q02078 (/ISS) Q5REW7 (/ISS) |
Ventricular cardiac myofibril assembly GO:0055005
The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q02078 (/ISS) Q02078 (/ISS) Q5REW7 (/ISS) |
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q02078 (/ISS) Q02078 (/ISS) Q5REW7 (/ISS) |
ERK5 cascade GO:0070375
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
7 | A2ICN5 (/ISS) A2VDZ3 (/ISS) F6XZU9 (/ISS) F6XZU9 (/ISS) Q2MJT0 (/ISS) Q5REW7 (/ISS) Q60929 (/ISS) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | A0A096MJY4 (/IMP) O89038 (/IMP) Q2MJT0 (/IMP) Q8CFN5 (/IMP) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | O55087 (/ISO) Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
4 | Q02078 (/IDA) Q02078 (/IDA) Q2MJT0 (/IDA) Q8CFN5 (/IDA) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q60929 (/IGI) Q63943 (/IGI) Q8CFN5 (/IGI) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q02078 (/IDA) Q02078 (/IDA) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q8CFN5 (/IGI) Q9U325 (/IGI) |
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q60929 (/ISO) Q8CFN5 (/ISO) |
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
2 | Q60929 (/ISO) Q8CFN5 (/ISO) |
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
2 | Q63943 (/IGI) Q8CFN5 (/IGI) |
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
|
2 | Q63943 (/IGI) Q8CFN5 (/IGI) |
Chondrocyte differentiation GO:0002062
The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
|
2 | Q63943 (/IGI) Q8CFN5 (/IGI) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
2 | Q02078 (/NAS) Q02078 (/NAS) |
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
|
2 | P40791 (/IMP) Q8CFN5 (/IMP) |
Positive regulation of cardiac muscle hypertrophy GO:0010613
Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
|
2 | Q02078 (/IDA) Q02078 (/IDA) |
Positive regulation of cardiac muscle hypertrophy GO:0010613
Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
|
2 | Q02078 (/IGI) Q02078 (/IGI) |
Positive regulation of cardiac muscle hypertrophy GO:0010613
Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
|
2 | Q60929 (/ISO) Q8CFN5 (/ISO) |
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
2 | Q63943 (/IMP) Q8CFN5 (/IMP) |
ERK5 cascade GO:0070375
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
2 | Q02078 (/IMP) Q02078 (/IMP) |
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
2 | A0A096MJY4 (/IEP) Q2MJT0 (/IEP) |
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
1 | Q60929 (/IMP) |
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
1 | Q8CFN5 (/IMP) |
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
1 | Q8CFN5 (/IEP) |
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
|
1 | Q8CFN5 (/IMP) |
B cell homeostasis GO:0001782
The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
|
1 | Q8CFN5 (/IMP) |
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
1 | Q8CFN5 (/IMP) |
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
|
1 | Q8CFN5 (/IMP) |
Blood vessel remodeling GO:0001974
The reorganization or renovation of existing blood vessels.
|
1 | Q8CFN5 (/IMP) |
Germinal center formation GO:0002467
The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
|
1 | Q8CFN5 (/IMP) |
Regulation of germinal center formation GO:0002634
Any process that modulates the frequency, rate, or extent of germinal center formation.
|
1 | Q8CFN5 (/IMP) |
Primary heart field specification GO:0003138
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.
|
1 | Q8CFN5 (/IMP) |
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
|
1 | Q8CFN5 (/IMP) |
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
1 | Q8CFN5 (/IGI) |
Sinoatrial valve morphogenesis GO:0003185
The process in which the structure of the sinoatrial valve is generated and organized.
|
1 | Q8CFN5 (/IMP) |
Cardiac ventricle formation GO:0003211
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
1 | Q8CFN5 (/IGI) |
Cardiac ventricle formation GO:0003211
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
1 | Q8CFN5 (/IMP) |
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
1 | Q60929 (/ISO) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8CFN5 (/ISO) |
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
1 | Q8CFN5 (/IMP) |
Anterior midgut development GO:0007496
The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.
|
1 | P40791 (/IMP) |
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | P40791 (/IEP) |
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | P40791 (/IMP) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P40791 (/TAS) |
Adult heart development GO:0007512
The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.
|
1 | Q14814 (/IEP) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
1 | P40791 (/IMP) |
Myoblast fusion GO:0007520
A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | P40791 (/IMP) |
Muscle cell fate determination GO:0007521
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.
|
1 | Q8CFN5 (/IMP) |
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
|
1 | Q8CFN5 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | Q03414 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | Q9PSD8 (/ISS) |
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P40791 (/IMP) |
Positive regulation of cardiac muscle hypertrophy GO:0010613
Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
|
1 | A0A096MJY4 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q8CFN5 (/ISO) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of alkaline phosphatase activity GO:0010694
Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
|
1 | Q8CFN5 (/IMP) |
Neural crest cell differentiation GO:0014033
The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
|
1 | Q8CFN5 (/IMP) |
Regulation of acetylcholine secretion, neurotransmission GO:0014056
Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
|
1 | Q9U325 (/IGI) |
Cardiac muscle hypertrophy in response to stress GO:0014898
The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.
|
1 | Q8CFN5 (/IMP) |
Regulation of striated muscle tissue development GO:0016202
Any process that modulates the frequency, rate or extent of striated muscle development.
|
1 | P40791 (/TAS) |
Antimicrobial humoral response GO:0019730
An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
|
1 | P40791 (/IMP) |
Lipid storage GO:0019915
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
|
1 | P40791 (/IMP) |
Dentate gyrus development GO:0021542
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
|
1 | A0A096MJY4 (/IEP) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q8CFN5 (/IMP) |
Platelet formation GO:0030220
The process in which platelets bud from long processes extended by megakaryocytes.
|
1 | Q8CFN5 (/IMP) |
Monocyte differentiation GO:0030224
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
|
1 | Q8CFN5 (/IMP) |
Negative regulation of ossification GO:0030279
Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
1 | Q8CFN5 (/ISO) |
Melanocyte differentiation GO:0030318
The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of bone mineralization GO:0030501
Any process that activates or increases the frequency, rate or extent of bone mineralization.
|
1 | Q8CFN5 (/IMP) |
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
|
1 | P40791 (/TAS) |
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
1 | Q8CFN5 (/IMP) |
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
1 | A0A096MJY4 (/IEP) |
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
1 | P40791 (/IDA) |
Response to vitamin E GO:0033197
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
|
1 | A0A096MJY4 (/IEP) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q8CFN5 (/IDA) |
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
1 | Q8CFN5 (/NAS) |
Cellular response to trichostatin A GO:0035984
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
|
1 | Q8CFN5 (/IDA) |
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
|
1 | Q8CFN5 (/IMP) |
Regulation of neuron apoptotic process GO:0043523
Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
|
1 | Q8CFN5 (/IMP) |
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
|
1 | Q8CFN5 (/IDA) |
Negative regulation of blood vessel endothelial cell migration GO:0043537
Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
1 | Q8CFN5 (/ISO) |
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
|
1 | Q8CFN5 (/IMP) |
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
|
1 | P40791 (/IMP) |
Regulation of megakaryocyte differentiation GO:0045652
Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | Q8CFN5 (/ISO) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q8CFN5 (/IDA) |
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
|
1 | Q60929 (/IDA) |
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
|
1 | Q8CFN5 (/IMP) |
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
1 | Q8CFN5 (/IMP) |
Mitochondrion distribution GO:0048311
Any process that establishes the spatial arrangement of mitochondria between and within cells.
|
1 | Q60929 (/IMP) |
Positive regulation of skeletal muscle tissue development GO:0048643
Any process that activates, maintains or increases the rate of skeletal muscle tissue development.
|
1 | Q8CFN5 (/ISO) |
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
1 | Q8CFN5 (/IMP) |
Cell morphogenesis involved in neuron differentiation GO:0048667
The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
|
1 | Q8CFN5 (/IMP) |
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
1 | Q8CFN5 (/IMP) |
Embryonic skeletal system morphogenesis GO:0048704
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
|
1 | Q8CFN5 (/IMP) |
Muscle fiber development GO:0048747
The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
|
1 | P40791 (/IMP) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
1 | Q2MJT0 (/IMP) |
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
1 | Q60929 (/ISO) |
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
|
1 | Q8CFN5 (/IMP) |
B cell receptor signaling pathway GO:0050853
A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
|
1 | Q8CFN5 (/IMP) |
Smooth muscle cell differentiation GO:0051145
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
|
1 | Q8CFN5 (/IMP) |
Regulation of synapse assembly GO:0051963
Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | Q8CFN5 (/IMP) |
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
|
1 | Q8CFN5 (/IMP) |
Carbohydrate storage GO:0052576
The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
|
1 | P40791 (/IMP) |
Ventricular cardiac myofibril assembly GO:0055005
The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
1 | Q60929 (/IMP) |
Cardiac muscle cell differentiation GO:0055007
The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
|
1 | Q8CFN5 (/NAS) |
Ventricular cardiac muscle cell differentiation GO:0055012
The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
|
1 | Q8CFN5 (/IMP) |
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
|
1 | Q8CFN5 (/IGI) |
Regulation of synaptic activity GO:0060025
Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of cardiac muscle cell proliferation GO:0060045
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
|
1 | Q8CFN5 (/IMP) |
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
|
1 | Q8CFN5 (/IMP) |
Transdifferentiation GO:0060290
The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.
|
1 | A0A096MJY4 (/IMP) |
Transdifferentiation GO:0060290
The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.
|
1 | Q8CFN5 (/ISO) |
Regulation of sarcomere organization GO:0060297
Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q8CFN5 (/IMP) |
Regulation of dendritic spine development GO:0060998
Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
|
1 | Q8CFN5 (/IMP) |
Renal tubule morphogenesis GO:0061333
The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
|
1 | Q8CFN5 (/IMP) |
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
1 | Q60929 (/IMP) |
ERK5 cascade GO:0070375
An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
1 | Q60929 (/ISO) |
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | Q8CFN5 (/IDA) |
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q60929 (/ISO) |
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
1 | A0A096MJY4 (/IDA) |
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
1 | Q8CFN5 (/ISO) |
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | A0A096MJY4 (/IDA) |
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | Q8CFN5 (/ISO) |
Cellular response to parathyroid hormone stimulus GO:0071374
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
|
1 | Q8CFN5 (/ISO) |
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | A0A096MJY4 (/IEP) |
Cellular response to fluid shear stress GO:0071498
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
|
1 | Q8CFN5 (/IDA) |
Cellular response to transforming growth factor beta stimulus GO:0071560
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
|
1 | Q8CFN5 (/ISO) |
Positive regulation of cell proliferation in bone marrow GO:0071864
A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
|
1 | Q8CFN5 (/IGI) |
Glomerulus morphogenesis GO:0072102
The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
|
1 | Q8CFN5 (/IMP) |
Nephron tubule epithelial cell differentiation GO:0072160
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of protein homodimerization activity GO:0090073
Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
|
1 | Q8CFN5 (/IDA) |
Negative regulation of vascular smooth muscle cell proliferation GO:1904706
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | Q8CFN5 (/ISO) |
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | Q14814 (/IGI) |
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | Q63943 (/ISO) |
Negative regulation of vascular associated smooth muscle cell migration GO:1904753
Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
|
1 | Q8CFN5 (/ISO) |
Negative regulation of vascular endothelial cell proliferation GO:1905563
Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.
|
1 | Q8CFN5 (/ISO) |
Positive regulation of macrophage apoptotic process GO:2000111
Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.
|
1 | Q8CFN5 (/IMP) |
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
|
1 | Q8CFN5 (/IMP) |
Regulation of AMPA receptor activity GO:2000311
Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of cardiac muscle cell differentiation GO:2000727
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of cardiac muscle cell differentiation GO:2000727
Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
|
1 | Q8CFN5 (/ISO) |
Positive regulation of behavioral fear response GO:2000987
Any process that activates or increases the frequency, rate or extent of behavioral fear response.
|
1 | Q8CFN5 (/IMP) |
Epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013
Any epithelial cell proliferation that is involved in renal tubule morphogenesis.
|
1 | Q8CFN5 (/IMP) |
Positive regulation of skeletal muscle cell differentiation GO:2001016
Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
|
1 | Q8CFN5 (/ISO) |
There are 27 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
129 |
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
(119 more) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
124 |
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
A0A024RAL6 (/IDA)
(114 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
77 |
A2ICN5 (/ISS)
A2VDZ3 (/ISS)
A4UTP7 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
E2R4Q4 (/ISS)
(67 more) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
55 |
A0A096MJY4 (/ISS)
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(45 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
54 |
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(44 more) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
54 |
A4UTP7 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
F1PAY8 (/ISS)
(44 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
37 |
A0A096MJY4 (/IDA)
O89038 (/IDA)
P40791 (/IDA)
Q02078 (/IDA)
Q02078 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(27 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
29 |
Q02078 (/TAS)
Q02078 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
Q06413 (/TAS)
(19 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
27 |
A0A096MJY4 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(17 more) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
25 |
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
Q06413 (/IDA)
(15 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | O55087 (/IC) Q03414 (/IC) Q60929 (/IC) Q63943 (/IC) Q8CFN5 (/IC) Q9PSD8 (/IC) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A0S2Z417 (/IDA) A0A0S2Z454 (/IDA) A0A0S2Z4N0 (/IDA) Q02078 (/IDA) Q02078 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | O55087 (/ISO) Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
4 | Q02078 (/IDA) Q02078 (/IDA) Q02080 (/IDA) Q02080 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | Q60929 (/ISO) Q63943 (/ISO) Q8CFN5 (/ISO) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | Q02078 (/ISS) Q02078 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q02080 (/TAS) Q02080 (/TAS) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
2 | O55087 (/ISO) Q60929 (/ISO) |
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
2 | Q63943 (/ISO) Q8CFN5 (/ISO) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | Q60929 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8CFN5 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q60929 (/ISO) |
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
1 | Q8CFN5 (/ISO) |
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | A0A096MJY4 (/IDA) |
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q8CFN5 (/ISO) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q8CFN5 (/ISO) |