The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"NIF3 (NGG1p interacting factor 3)-like
".
FunFam 1: GTP cyclohydrolase 1 type 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q9EQ80 (/IPI) Q9GZT8 (/IPI) Q9GZT8 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | Q9GZT8 (/IPI) Q9GZT8 (/IPI) Q9NK57 (/IPI) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | Q9GZT8 (/IPI) Q9GZT8 (/IPI) |
|
GTP cyclohydrolase activity GO:0003933
Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
|
1 | O94404 (/ISM) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
1 | Q9EQ80 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9EQ80 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
4 | Q05B89 (/ISS) Q4V7D6 (/ISS) Q9GZT8 (/ISS) Q9GZT8 (/ISS) |
|
Negative regulation of nucleic acid-templated transcription GO:1903507
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
|
4 | Q05B89 (/ISS) Q4V7D6 (/ISS) Q9GZT8 (/ISS) Q9GZT8 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q9GZT8 (/IDA) Q9GZT8 (/IDA) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q9EQ80 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9EQ80 (/ISO) |
|
Negative regulation of nucleic acid-templated transcription GO:1903507
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
|
1 | Q9EQ80 (/IDA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
13 |
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
P53081 (/IDA)
Q384V6 (/IDA)
(3 more) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
10 | P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) Q9EQ80 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) P53081 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
9 | P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) P53081 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q05B89 (/ISS) Q4V7D6 (/ISS) Q9GZT8 (/ISS) Q9GZT8 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q05B89 (/ISS) Q4V7D6 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O94404 (/HDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9EQ80 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9EQ80 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O94404 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O94404 (/HDA) |
