The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
SUI1-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Sui1 translation initiation factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Translation initiation factor binding GO:0031369
Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Translation initiation factor binding GO:0031369
Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
7 P32911 (/IPI) P32911 (/IPI) P32911 (/IPI) P32911 (/IPI) P32911 (/IPI) P32911 (/IPI) P32911 (/IPI)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
1 P79060 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formation of translation preinitiation complex GO:0001731
The joining of the small ribosomal subunit, ternary complex, and mRNA.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Maintenance of translational fidelity GO:1990145
Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.
7 P32911 (/IMP) P32911 (/IMP) P32911 (/IMP) P32911 (/IMP) P32911 (/IMP) P32911 (/IMP) P32911 (/IMP)
Cytoplasmic translational initiation GO:0002183
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
1 P79060 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Multi-eIF complex GO:0043614
A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.
7 P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA) P32911 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P79060 (/HDA)
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