The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Elongation Factor G (Translational Gtpase), domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Translation factor GUF1, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
152 P46943 (/IDA) P46943 (/IDA) P46943 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(142 more)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
149 P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI)
(139 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
149 P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI) P60785 (/IPI)
(139 more)
Ribosomal large subunit binding GO:0043023
Interacting selectively and non-covalently with any part of the larger ribosomal subunit.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
Ribosomal small subunit binding GO:0043024
Interacting selectively and non-covalently with any part of the small ribosomal subunit.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
10 O13869 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS) Q9KPB0 (/ISS)
Mitochondrial ribosome binding GO:0097177
Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell.
3 P46943 (/IDA) P46943 (/IDA) P46943 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q38BU9 (/ISM) Q38BU9 (/ISM)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
2 Q9FNM5 (/IPI) Q9FNM5 (/IPI)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 O13869 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 B0G189 (/ISS)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
1 O13869 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
Response to pH GO:0009268
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
149 P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP)
(139 more)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
149 P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP)
(139 more)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
149 P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP) P60785 (/IMP)
(139 more)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
3 P46943 (/IMP) P46943 (/IMP) P46943 (/IMP)
Positive regulation of mitochondrial translation GO:0070131
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
1 O13869 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
149 P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA) P60785 (/IDA)
(139 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA) P9WK97 (/HDA)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 O13869 (/HDA) P46943 (/HDA) P46943 (/HDA) P46943 (/HDA) Q8C3X4 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P46943 (/HDA) P46943 (/HDA) P46943 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
3 P46943 (/IDA) P46943 (/IDA) P46943 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q38BU9 (/IDA) Q38BU9 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q38BU9 (/RCA) Q38BU9 (/RCA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9FNM5 (/IDA) Q9FNM5 (/IDA)
Kinetoplast GO:0020023
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
2 Q38BU9 (/IDA) Q38BU9 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 B0G189 (/ISS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 O13869 (/ISO)
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