The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Elongation Factor G (Translational Gtpase), domain 3
".
FunFam 28: Pre-mRNA-splicing factor SNU114
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
3 | P36048 (/IMP) P36048 (/IMP) P36048 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | P36048 (/IPI) P36048 (/IPI) P36048 (/IPI) |
|
U5 snRNA binding GO:0030623
Interacting selectively and non-covalently with the U5 small nuclear RNA (U5 snRNA).
|
3 | P36048 (/IDA) P36048 (/IDA) P36048 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Spliceosomal tri-snRNP complex assembly GO:0000244
The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
|
3 | P36048 (/IMP) P36048 (/IMP) P36048 (/IMP) |
|
Generation of catalytic spliceosome for first transesterification step GO:0000349
Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
|
3 | P36048 (/IGI) P36048 (/IGI) P36048 (/IGI) |
|
Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) GO:0000388
Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
|
3 | P36048 (/IMP) P36048 (/IMP) P36048 (/IMP) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
3 | P36048 (/IMP) P36048 (/IMP) P36048 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P36048 (/HDA) P36048 (/HDA) P36048 (/HDA) |
|
U5 snRNP GO:0005682
A ribonucleoprotein complex that contains small nuclear RNA U5.
|
3 | P36048 (/IDA) P36048 (/IDA) P36048 (/IDA) |
|
U4/U6 x U5 tri-snRNP complex GO:0046540
A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.
|
3 | P36048 (/IDA) P36048 (/IDA) P36048 (/IDA) |
