The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 981: NPL3p RNA-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
6 Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
6 Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI)
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Eukaryotic initiation factor 4G binding GO:0031370
Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI) Q01560 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
6 Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI)
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
6 Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI)
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
6 Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI) Q01560 (/IGI)
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)
Negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled GO:2000805
Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled GO:2000805
Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA) Q01560 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP) Q01560 (/IMP)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
6 Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA) Q01560 (/IDA)
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