The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 226: Non-POU domain-containing octamer-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
E-box binding GO:0070888
Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
29 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(19 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
17 Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI)
(7 more)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
14 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(4 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
14 Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA) Q15233 (/ISA)
(4 more)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
14 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(4 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
14 Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA)
(4 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
14 Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI) Q15233 (/IPI)
(4 more)
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
2 Q99K48 (/IDA) Q99K48 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 Q99K48 (/IDA) Q99K48 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q99K48 (/ISO) Q99K48 (/ISO)
E-box binding GO:0070888
Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
2 Q99K48 (/IDA) Q99K48 (/IDA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
30 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(20 more)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
29 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(19 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
29 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(19 more)
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
14 Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA)
(4 more)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
14 Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS)
(4 more)
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
14 Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS)
(4 more)
Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway GO:1903377
Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
14 Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA)
(4 more)
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
2 Q99K48 (/IMP) Q99K48 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q99K48 (/IDA) Q99K48 (/IDA)
Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway GO:1903377
Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q5FVM4 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
29 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(19 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
28 A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA) A0A0S2Z4Z9 (/IDA)
(18 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
16 Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA)
(6 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
14 Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS) Q15233 (/TAS)
(4 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
14 Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA) Q15233 (/HDA)
(4 more)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
14 Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA)
(4 more)
Paraspeckles GO:0042382
Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.
14 Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA) Q15233 (/IDA)
(4 more)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
14 Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS) Q15233 (/ISS)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
2 Q99K48 (/ISO) Q99K48 (/ISO)
Paraspeckles GO:0042382
Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.
2 Q99K48 (/ISO) Q99K48 (/ISO)
RNA polymerase II transcription factor complex GO:0090575
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
2 Q99K48 (/IDA) Q99K48 (/IDA)
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