The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Probable polyketide synthase Pks8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
14 I6XD69 (/IPI) I6XD69 (/IPI) Q6DNE2 (/IPI) Q6DNE2 (/IPI) Q6DNE3 (/IPI) Q6DNE3 (/IPI) Q6DNE5 (/IPI) Q6DNE5 (/IPI) Q6DNE7 (/IPI) Q6DNF2 (/IPI)
(4 more)
Phosphopantetheine binding GO:0031177
Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).
11 Q03131 (/TAS) Q03131 (/TAS) Q03133 (/TAS) Q03133 (/TAS) Q9ZGI2 (/TAS) Q9ZGI3 (/TAS) Q9ZGI4 (/TAS) Q9ZGI4 (/TAS) Q9ZGI5 (/TAS) Q9ZGI5 (/TAS)
(1 more)
Transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747
Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
7 Q9ZGI2 (/IDA) Q9ZGI3 (/IDA) Q9ZGI4 (/IDA) Q9ZGI4 (/IDA) Q9ZGI5 (/IDA) Q9ZGI5 (/IDA) Q9ZGI5 (/IDA)
Erythronolide synthase activity GO:0047879
Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.
4 Q03131 (/IDA) Q03131 (/IDA) Q03133 (/IDA) Q03133 (/IDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Macrolide biosynthetic process GO:0033068
The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
11 Q03131 (/IDA) Q03131 (/IDA) Q03133 (/IDA) Q03133 (/IDA) Q9ZGI2 (/IDA) Q9ZGI3 (/IDA) Q9ZGI4 (/IDA) Q9ZGI4 (/IDA) Q9ZGI5 (/IDA) Q9ZGI5 (/IDA)
(1 more)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
8 O86335 (/IMP) O86335 (/IMP) O86335 (/IMP) P96285 (/IMP) P96285 (/IMP) P96285 (/IMP) Q7TXK8 (/IMP) Q7TXK8 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
7 O86335 (/IMP) O86335 (/IMP) O86335 (/IMP) P94996 (/IMP) P94996 (/IMP) P94996 (/IMP) P94996 (/IMP)
DIM/DIP cell wall layer assembly GO:0071770
The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
7 P94996 (/IMP) P94996 (/IMP) P94996 (/IMP) P94996 (/IMP) P96285 (/IMP) P96285 (/IMP) P96285 (/IMP)
Actinobacterium-type cell wall biogenesis GO:0071766
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
5 P96285 (/IMP) P96285 (/IMP) P96285 (/IMP) Q7TXK8 (/IMP) Q7TXK8 (/IMP)
Macrolide biosynthetic process GO:0033068
The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
3 Q9ZGI5 (/IMP) Q9ZGI5 (/IMP) Q9ZGI5 (/IMP)
Growth of symbiont in host cell GO:0044119
The increase in size or mass of symbiont, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
3 O86335 (/IMP) O86335 (/IMP) O86335 (/IMP)
Unsaturated fatty acid biosynthetic process GO:0006636
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
2 O65933 (/IMP) O65933 (/IMP)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
2 Q4KCY8 (/IC) Q4KCY8 (/IC)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
2 Q4KCY8 (/IGC) Q4KCY8 (/IGC)
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
1 B2HIL7 (/IDA)
Actinobacterium-type cell wall biogenesis GO:0071766
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
1 B2HIL7 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 P94996 (/HDA) P94996 (/HDA) P94996 (/HDA) P94996 (/HDA) P96285 (/HDA) P96285 (/HDA) P96285 (/HDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
4 P94996 (/HDA) P94996 (/HDA) P94996 (/HDA) P94996 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P94996 (/HDA) P94996 (/HDA) P94996 (/HDA) P94996 (/HDA)
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
2 Q7TXK8 (/IMP) Q7TXK8 (/IMP)
Polyketide synthase complex GO:0034081
A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
1 B2HIL7 (/IDA)
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