The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Caspase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Non-catalytic caspase homolog csp-3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027
Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
2 G5ECW5 (/IMP) Q9TZP5 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 G5ECW5 (/IPI)
Zymogen binding GO:0035375
Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
1 G5ECW5 (/IMP)
Caspase binding GO:0089720
Interacting selectively and non-covalently with a caspase family protein.
1 G5ECW5 (/IPI)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 G5ECW5 (/IGI) Q9TZP5 (/IGI)
Positive regulation of apoptotic process involved in development GO:1904747
Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.
2 G5ECW5 (/IGI) Q9TZP5 (/IGI)
Inhibition of cysteine-type endopeptidase activity involved in apoptotic process GO:1990001
Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.
2 G5ECW5 (/IMP) Q9TZP5 (/IMP)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
1 G5ECW5 (/IGI)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
1 G5ECW5 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 G5ECW5 (/IMP)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 G5ECW5 (/IMP)
Positive regulation of locomotion involved in locomotory behavior GO:0090326
Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
1 G5ECW5 (/IMP)
Positive regulation of brood size GO:0090727
Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
1 Q9TZP5 (/IMP)
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
1 G5ECW5 (/IGI)
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
1 G5ECW5 (/IMP)
Negative regulation of apoptotic process involved in development GO:1904746
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.
1 G5ECW5 (/IMP)
Positive regulation of fertilization GO:1905516
Any process that activates or increases the frequency, rate or extent of fertilization.
1 Q9TZP5 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 G5ECW5 (/IDA)
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