The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"MHC class I-like antigen recognition-like
".
FunFam 4: Retinoic acid early-inducible protein 1-beta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | O08603 (/IPI) O08604 (/IPI) Q5VY80 (/IPI) Q6H3X3 (/IPI) Q8TD07 (/IPI) Q9BZM4 (/IPI) Q9BZM5 (/IPI) Q9BZM6 (/IPI) Q9JI58 (/IPI) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
9 | O08602 (/IDA) O08603 (/IDA) O08604 (/IDA) Q9BZM4 (/IDA) Q9BZM5 (/IDA) Q9BZM6 (/IDA) Q9CZQ6 (/IDA) Q9CZQ6 (/IDA) Q9JI58 (/IDA) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
5 | C5IXG6 (/IPI) Q6H3X3 (/IPI) Q8TD07 (/IPI) Q9CZQ6 (/IPI) Q9CZQ6 (/IPI) |
|
Natural killer cell lectin-like receptor binding GO:0046703
Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
|
3 | Q9CZQ6 (/ISO) Q9CZQ6 (/ISO) Q9JI58 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Natural killer cell mediated cytotoxicity GO:0042267
The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
6 | Q6H3X3 (/IDA) Q8TD07 (/IDA) Q9BZM4 (/IDA) Q9BZM5 (/IDA) Q9BZM6 (/IDA) Q9JI58 (/IDA) |
|
Natural killer cell activation GO:0030101
The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
|
3 | Q9BZM4 (/IDA) Q9BZM5 (/IDA) Q9BZM6 (/IDA) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
3 | O08602 (/IDA) O08603 (/IDA) O08604 (/IDA) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
3 | C5IXG6 (/IDA) Q6AYE9 (/IDA) Q8TD07 (/IDA) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
3 | Q8TD07 (/TAS) Q9BZM4 (/TAS) Q9BZM6 (/TAS) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
3 | O08602 (/IDA) O08603 (/IDA) O08604 (/IDA) |
|
Cellular response to exogenous dsRNA GO:0071360
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
|
3 | O08602 (/IDA) O08603 (/IDA) O08604 (/IDA) |
|
T cell mediated cytotoxicity GO:0001913
The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
|
2 | Q9CZQ6 (/IDA) Q9CZQ6 (/IDA) |
|
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
|
2 | Q9CZQ6 (/ISS) Q9CZQ6 (/ISS) |
|
Positive regulation of natural killer cell cytokine production GO:0002729
Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
|
1 | Q6H3X3 (/IDA) |
|
Positive regulation of immune response to tumor cell GO:0002839
Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
|
1 | O08603 (/IDA) |
|
Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
|
1 | C5IXG6 (/IMP) |
|
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
|
1 | O08603 (/IDA) |
|
Positive regulation of natural killer cell activation GO:0032816
Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
|
1 | O08603 (/IDA) |
|
Susceptibility to natural killer cell mediated cytotoxicity GO:0042271
The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
|
1 | O08603 (/IDA) |
|
Positive regulation of macrophage activation GO:0043032
Any process that stimulates, induces or increases the rate of macrophage activation.
|
1 | O08603 (/IDA) |
|
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
|
1 | O08603 (/IDA) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
7 | O08602 (/IDA) O08603 (/IDA) O08604 (/IDA) Q9BZM4 (/IDA) Q9BZM5 (/IDA) Q9BZM6 (/IDA) Q9JI58 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | Q5VY80 (/TAS) Q6H3X3 (/TAS) Q8TD07 (/TAS) Q9BZM4 (/TAS) Q9BZM5 (/TAS) Q9BZM6 (/TAS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
3 | Q5VY80 (/TAS) Q6H3X3 (/TAS) Q9BZM5 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
3 | O08603 (/IDA) O08604 (/IDA) Q9JI58 (/IDA) |
|
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
|
3 | Q9CZQ6 (/ISO) Q9CZQ6 (/ISO) Q9JI58 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q6H3X3 (/NAS) Q8TD07 (/NAS) |
|
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
2 | Q9CZQ6 (/ISS) Q9CZQ6 (/ISS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9BZM5 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9BZM6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9BZM6 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q9BZM5 (/IDA) |
|
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | Q9BZM6 (/IDA) |
|
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
|
1 | O08603 (/IDA) |
|
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
|
1 | C5IXG6 (/IDA) |
